Alzheimer's disease – An overview of nano herbal formulations

Vishal Shivaji Patil , Swapnali Sachin Patil , Snehal Rajendra Patil , Akanksha Shahaji Pawar , Amol Somnath Shete
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Abstract

Background

The progressive neurological condition known as Alzheimer’s disease (AD) mainly affects elderly persons. Memory loss, cognitive decline, and the build-up of beta-amyloid (Aβ) plaques and neurofibrillary tangles in the brain are some of its distinguishing characteristics. The benefits of current treatment choices are limited, generally fail to effectively stop progression of the disease, and are typically linked to adverse effects that lower quality of life.

Main body

Herbal medicines are viable solutions for treating AD, according to recent research, especially when paired with nanotechnology. These formulations seek to overcome important issues with traditional treatments, such as poor permeability and low solubility across the blood-brain barrier (BBB). When used with herbal medicine, nanotechnology provides creative answers to these problems that may improve therapeutic delivery and efficacy. With an emphasis on their use in treatment of AD, this paper examines the relationship between herbal medicine and nanotechnology. It looks at the legal environment and intellectual property rights surrounding herbal nanoformulations, emphasizing need for more thorough research to fully comprehend their modes of action and prospective applications. Additionally, it compiles information on patents and ongoing studies, offering a summary of developments in area.

Conclusion

The therapy of Alzheimer's disease can be revolutionized by incorporating herbal treatments into nanostructured compositions. Such advances have the potential to transform treatment approaches by boosting therapeutic results and delivery systems. This review highlights the significance of ongoing research and development in this area, providing promise for improved outcomes and more efficient management of Alzheimer's disease patients.
阿尔茨海默病-纳米草药配方概述
背景:被称为阿尔茨海默病(AD)的进行性神经系统疾病主要影响老年人。记忆丧失、认知能力下降、β -淀粉样蛋白(Aβ)斑块和脑神经纤维缠结的形成是其显著特征。目前治疗选择的益处是有限的,通常不能有效地阻止疾病的进展,并且通常与降低生活质量的不良反应有关。根据最近的研究,草药是治疗阿尔茨海默病的可行方法,特别是当与纳米技术结合使用时。这些配方旨在克服传统治疗方法的重要问题,例如血脑屏障(BBB)渗透性差和溶解度低。当与草药一起使用时,纳米技术为这些问题提供了创造性的答案,可能会改善治疗效果。本文重点介绍了它们在治疗阿尔茨海默病中的应用,探讨了草药与纳米技术之间的关系。它着眼于围绕草药纳米配方的法律环境和知识产权,强调需要更彻底的研究来充分理解它们的作用模式和潜在的应用。此外,它还汇编有关专利和正在进行的研究的信息,提供该领域发展的摘要。结论在纳米结构药物中加入草药治疗阿尔茨海默病可能会带来革命性的变化。这些进展有可能通过提高治疗效果和给药系统来改变治疗方法。这篇综述强调了这一领域正在进行的研究和开发的重要性,为改善阿尔茨海默病患者的预后和更有效的管理提供了希望。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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