{"title":"Alzheimer's disease – An overview of nano herbal formulations","authors":"Vishal Shivaji Patil , Swapnali Sachin Patil , Snehal Rajendra Patil , Akanksha Shahaji Pawar , Amol Somnath Shete","doi":"10.1016/j.prerep.2025.100042","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>The progressive neurological condition known as Alzheimer’s disease (AD) mainly affects elderly persons. Memory loss, cognitive decline, and the build-up of beta-amyloid (Aβ) plaques and neurofibrillary tangles in the brain are some of its distinguishing characteristics. The benefits of current treatment choices are limited, generally fail to effectively stop progression of the disease, and are typically linked to adverse effects that lower quality of life.</div></div><div><h3>Main body</h3><div>Herbal medicines are viable solutions for treating AD, according to recent research, especially when paired with nanotechnology. These formulations seek to overcome important issues with traditional treatments, such as poor permeability and low solubility across the blood-brain barrier (BBB). When used with herbal medicine, nanotechnology provides creative answers to these problems that may improve therapeutic delivery and efficacy. With an emphasis on their use in treatment of AD, this paper examines the relationship between herbal medicine and nanotechnology. It looks at the legal environment and intellectual property rights surrounding herbal nanoformulations, emphasizing need for more thorough research to fully comprehend their modes of action and prospective applications. Additionally, it compiles information on patents and ongoing studies, offering a summary of developments in area.</div></div><div><h3>Conclusion</h3><div>The therapy of Alzheimer's disease can be revolutionized by incorporating herbal treatments into nanostructured compositions. Such advances have the potential to transform treatment approaches by boosting therapeutic results and delivery systems. This review highlights the significance of ongoing research and development in this area, providing promise for improved outcomes and more efficient management of Alzheimer's disease patients.</div></div>","PeriodicalId":101015,"journal":{"name":"Pharmacological Research - Reports","volume":"3 ","pages":"Article 100042"},"PeriodicalIF":0.0000,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pharmacological Research - Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2950200425000163","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Background
The progressive neurological condition known as Alzheimer’s disease (AD) mainly affects elderly persons. Memory loss, cognitive decline, and the build-up of beta-amyloid (Aβ) plaques and neurofibrillary tangles in the brain are some of its distinguishing characteristics. The benefits of current treatment choices are limited, generally fail to effectively stop progression of the disease, and are typically linked to adverse effects that lower quality of life.
Main body
Herbal medicines are viable solutions for treating AD, according to recent research, especially when paired with nanotechnology. These formulations seek to overcome important issues with traditional treatments, such as poor permeability and low solubility across the blood-brain barrier (BBB). When used with herbal medicine, nanotechnology provides creative answers to these problems that may improve therapeutic delivery and efficacy. With an emphasis on their use in treatment of AD, this paper examines the relationship between herbal medicine and nanotechnology. It looks at the legal environment and intellectual property rights surrounding herbal nanoformulations, emphasizing need for more thorough research to fully comprehend their modes of action and prospective applications. Additionally, it compiles information on patents and ongoing studies, offering a summary of developments in area.
Conclusion
The therapy of Alzheimer's disease can be revolutionized by incorporating herbal treatments into nanostructured compositions. Such advances have the potential to transform treatment approaches by boosting therapeutic results and delivery systems. This review highlights the significance of ongoing research and development in this area, providing promise for improved outcomes and more efficient management of Alzheimer's disease patients.