A killer in disguise: Button battery ingestions in acute care.

IF 2.6 4区医学 Q2 PHARMACOLOGY & PHARMACY

Current pharmaceutical design Pub Date : 2025-04-25 DOI:10.2174/0113816128361865250411045020

Canan Akman, Ozgur Karcioglu, Göksu Afacan Ozturk, Asli Bahar Ucar

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引用次数: 0

Abstract

Ingestion of button batteries (BB) represents a substantial health hazard, causing more common and severe complications than most other ingested objects. While the primary mechanism of injury is alkaline caustic injury (mediated by hydroxide ions produced through electrolysis at the site of the button battery), additional pathophysiological processes include pressure-induced necrosis, accumulation of hydroxide compounds at the battery's negative pole, direct caustic tissue injury, and potential heavy metal toxicity. Full-thickness burns, esophageal perforation, tracheoesophageal and aortoesophageal fistulas are encountered shortly after exposure. Vocal cord paralysis due to BB ingestion appears to be an early sign to predict the severity of the condition. Besides expedient removal, mitigation strategies are the key to the management. Pre-BB removal using honey or sucralfate and post-removal sterile acetic acid irrigation in the operation room can alleviate complication rates. This review is intended to cover and summarize all aspects of these incidents to provide information to clinicians and healthcare personnel.

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伪装的杀手：急症护理中的纽扣电池摄入。

吞下纽扣电池（BB）对健康构成重大危害，与大多数其他被吞下的物体相比，会引起更常见和更严重的并发症。虽然损伤的主要机制是碱性苛性性损伤（由电解产生的氢氧化物离子介导），但其他病理生理过程包括压力诱导的坏死、电池负极氢氧化物的积累、直接苛性性组织损伤和潜在的重金属毒性。暴露后不久就会出现全层烧伤、食管穿孔、气管食管瘘和主动脉食管瘘。由于摄取BB引起的声带麻痹似乎是预测病情严重程度的早期迹象。除了权宜之计，缓解策略是管理的关键。术前用蜂蜜或硫糖钠去除bb，术后在手术室用无菌乙酸冲洗可降低并发症发生率。本综述旨在涵盖和总结这些事件的所有方面，为临床医生和医护人员提供信息。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current pharmaceutical design 医学-药学

CiteScore

6.30

自引率

0.00%

发文量

302

审稿时长

2 months

期刊介绍： Current Pharmaceutical Design publishes timely in-depth reviews and research articles from leading pharmaceutical researchers in the field, covering all aspects of current research in rational drug design. Each issue is devoted to a single major therapeutic area guest edited by an acknowledged authority in the field. Each thematic issue of Current Pharmaceutical Design covers all subject areas of major importance to modern drug design including: medicinal chemistry, pharmacology, drug targets and disease mechanism.