Secular trends of vitamin D and calcium intake and their circulating levels in US adults from 2007 to 2018.

IF 4 2区农林科学 Q2 NUTRITION & DIETETICS

Frontiers in Nutrition Pub Date : 2025-03-19 eCollection Date: 2025-01-01 DOI:10.3389/fnut.2025.1538019

Yongliang Du, Chao Ma, Zhaoyue Shang, Xiaohua Zhang, Yanlin Duan, Tong Liu, Yang Yu, Shuman Yang

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引用次数: 0

Abstract

Background: Few studies have examined the secular trends of total calcium and vitamin D intake and their circulating levels together among adults in the United States (US). Understanding the trends of these nutrients may be useful for refining existing nutrition policy and guidelines.

Objective: The aim of this study was to report trends in total calcium and vitamin D intake and their circulating levels in the US population aged 18 years or older in 2007-2018.

Methods: This cross-sectional study identified adults aged 18 years or older in the US National Health and Nutrition Examination Survey (NHANES) from 2007 to 2018. Calcium and vitamin D intake including their supplements were the average of two 24-h recalls. Serum calcium and serum 25-hydroxyvitamin D [25(OH)D] were measured using established methods. Weighted regression was used to test trends in calcium and vitamin D intake, and serum total calcium and 25(OH)D levels.

Results: This research included 16,751 participants, including 9,046 males and 7,705 females. Serum total calcium significantly decreased with survey years from 2007 to 2018 (9.42 to 9.31 mg/dL) (P trend <0.001). Calcium intake declined from 2009 to 2018 (1,070 to 1,010 mg/day; P trend <0.001). In contrast, vitamin D intake and serum 25(OH)D increased with survey years (5.8 to 11.0 mcg/day and 65.6 to 68.5 nmol/L, respectively; all P trend <0.001). The trends in calcium intake vs. serum total calcium (P trend interaction =0.267), and vitamin D intake vs. serum 25(OH)D with survey years were comparable (P trend interaction =0.190). Inadequate vitamin D intake decreased with survey years (86.0 to 80.2%; P trend = 0.002). Moderate vitamin D deficiency (22.3 to 21.5%; P trend = 0.043), but not severe vitamin D deficiency (3.3 to 2.9%; P trend = 0.119), also declined with calendar years.

Conclusion: From 2007 to 2018, US adults showed a decrease in serum total calcium, and an increase in serum 25(OH)D levels. Both trends were partly due to declined calcium and increased vitamin D intake.

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2007年至2018年美国成年人维生素D和钙摄入量及其循环水平的长期趋势

背景：很少有研究调查了美国成年人钙和维生素D总摄入量及其循环水平的长期趋势。了解这些营养素的趋势可能有助于完善现有的营养政策和指导方针。目的：本研究的目的是报告2007-2018年美国18岁 以上人口钙和维生素D总摄入量及其循环水平的趋势。方法：本横断面研究确定了2007年至2018年美国国家健康与营养检查调查（NHANES）中18岁 及以上的成年人。钙和维生素D的摄入量，包括它们的补充剂，是24小时内两次的平均摄入量。采用既定方法测定血清钙和血清25-羟基维生素D [25(OH)D]。使用加权回归来检验钙和维生素D摄入量的趋势，以及血清总钙和25(OH)D水平。结果：这项研究包括16751名参与者，其中包括9046名男性和7705名女性。2007 - 2018年血清总钙随调查年份显著降低（9.42 ~ 9.31 mg/dL）（P趋势P趋势P趋势P趋势交互作用=0.267），维生素D摄入量与血清25(OH)D的交互作用与调查年份具有可比性（P趋势交互作用=0.190）。维生素D摄入不足随着调查年限的增加而减少(86.0 - 80.2%； 趋势= 0.002页)。中度维生素D缺乏症（22.3%至21.5%）；P趋势 = 0.043)，但没有严重的维生素D缺乏症(3.3%至2.9%；P趋势 = 0.119)，也随历年下降。结论：从2007年到2018年，美国成年人血清总钙水平下降，血清25(OH)D水平升高。这两种趋势的部分原因是钙的摄入量减少而维生素D的摄入量增加。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Frontiers in Nutrition Agricultural and Biological Sciences-Food Science

CiteScore

5.20

自引率

8.00%

发文量

2891

审稿时长

12 weeks

期刊介绍： No subject pertains more to human life than nutrition. The aim of Frontiers in Nutrition is to integrate major scientific disciplines in this vast field in order to address the most relevant and pertinent questions and developments. Our ambition is to create an integrated podium based on original research, clinical trials, and contemporary reviews to build a reputable knowledge forum in the domains of human health, dietary behaviors, agronomy & 21st century food science. Through the recognized open-access Frontiers platform we welcome manuscripts to our dedicated sections relating to different areas in the field of nutrition with a focus on human health. Specialty sections in Frontiers in Nutrition include, for example, Clinical Nutrition, Nutrition & Sustainable Diets, Nutrition and Food Science Technology, Nutrition Methodology, Sport & Exercise Nutrition, Food Chemistry, and Nutritional Immunology. Based on the publication of rigorous scientific research, we thrive to achieve a visible impact on the global nutrition agenda addressing the grand challenges of our time, including obesity, malnutrition, hunger, food waste, sustainability and consumer health.