Dermoscopic Aspects of Cutaneous Melanoma and Non-Melanoma Skin Cancer.

IF 2.6 4区 医学 Q2 PHARMACOLOGY & PHARMACY
Gabriela Fortes Escobar, Lucas Samuel Perinazzo Pauvels, Renato Marchiori Bakos
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引用次数: 0

Abstract

Dermoscopy is a very important diagnostic tool in clinical practice. It increases accuracy in skin cancer detection. Melanoma and its major variants have distinct dermoscopic patterns and structures described as well as cutaneous keratynocytic tumors such as basal cell carcinoma and squamous cell carcinomas. Superficial spreading melanoma may show dermoscopic structures varying from atypical network, atypical hyperpigmentation, atypical globules and dots, and atypical streaks to negative network; lentigo maligna lesions demonstrate dermoscopic structures associated with the tumour progression around follicular openings; nodular lesions may be suspected mainly by colors (pink or blue and black) and the recognition of peculiar patterns such as the parallel ridge pattern may facilitate vascular structures and acral lentiginous. The histopathologic subtype of BCC is an important determinant of the dermoscopic pattern of the tumor, being the vascular strucutures a significant clue for its diagnosis. Invasive squamous cell carcinoma may also be differentiated from in situ lesions by clinical and dermoscopic aspects such as vascular and hyperkeratotic structures. The aim of this review was to provide a comprehensive overview of the major dermoscopic patterns and structures described for the diagnosis of major melanoma variants and for cutaneous carcinomas. It also gives some insights about sequential digital imaging for patients with multiple melanocytic nevi.

皮肤黑色素瘤和非黑色素瘤皮肤癌的皮肤镜观察。
皮肤镜检查是临床上非常重要的诊断工具。它提高了皮肤癌检测的准确性。黑色素瘤及其主要变体具有不同的皮肤镜模式和结构,以及皮肤角质细胞瘤,如基底细胞癌和鳞状细胞癌。浅表扩散黑色素瘤可表现为非典型网状、非典型色素沉着、非典型球状和圆点、非典型条纹到阴性网状的皮肤镜结构;Lentigo恶性病变显示皮肤镜下结构与卵泡开口周围肿瘤进展相关;结节性病变可能主要通过颜色(粉红色或蓝黑色)来怀疑,识别特殊的图案,如平行脊纹,可能有助于血管结构和肢端晶状体。BCC的组织病理学亚型是皮肤镜下肿瘤类型的重要决定因素,血管结构是其诊断的重要线索。浸润性鳞状细胞癌也可以从临床和皮肤镜方面(如血管和角化过度结构)与原位病变区分开来。本综述的目的是提供一个全面的概述主要的皮肤镜模式和结构描述的主要黑色素瘤变异和皮肤癌的诊断。同时也对多发性黑素细胞痣患者的序贯数字成像提供了一些见解。
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来源期刊
CiteScore
6.30
自引率
0.00%
发文量
302
审稿时长
2 months
期刊介绍: Current Pharmaceutical Design publishes timely in-depth reviews and research articles from leading pharmaceutical researchers in the field, covering all aspects of current research in rational drug design. Each issue is devoted to a single major therapeutic area guest edited by an acknowledged authority in the field. Each thematic issue of Current Pharmaceutical Design covers all subject areas of major importance to modern drug design including: medicinal chemistry, pharmacology, drug targets and disease mechanism.
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