Borate-modified magnetic graphene oxide in enrichment and purification of cis-diols compound from natural extract

IF 8.5 1区农林科学 Q1 CHEMISTRY, APPLIED

Food Chemistry Pub Date : 2025-04-03 DOI:10.1016/j.foodchem.2025.144199

Jingjing Zhang, Dan Wang, Xu Ni, Fangqi Wang, Donghao Liu, Linjie Zhao, Jie Gao, Wenjing Ren, Hua He, Deli Xiao, Pierre Dramou

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引用次数: 0

Abstract

Black tartary buckwheat, rich in rutin, has been traditionally used for treating cardiovascular diseases, yet its efficient separation remains challenging. Herein, magnetic graphene oxide (MGO) was functionalized with 3-aminophenylboronic acid (APBA) via EDC/NHS coupling, forming MGO@APBA for selective rutin enrichment. Magnetic solid-phase extraction (MSPE) coupled with high-performance liquid chromatography (HPLC-UV) was employed for rutin analysis. Adsorption performances suggest Langmuir isotherm and pseudo-second-order model as best fit (Q_m = 80.18 mg g⁻¹). High satisfactory recovery (98.9 %–101.9 %), low limit of detection (0.5 mg L⁻¹), wide linearity range (20–200 mg L⁻¹) and good coefficient of determination (R² = 0.994) were found. MGO@APBA demonstrated excellent selectivity through significant statistical (p = 0.03<0.05), reusability (>80 % adsorption efficiency after four cycles). MGO@APBA showed excellent selectivity and reusability, making it a promising tool for rutin purification. This study provides a strategy for rutin separation and highlights the potential of borate-functionalized nanomaterials in natural product extraction.

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来源期刊

Food Chemistry 工程技术-食品科技

CiteScore

16.30

自引率

10.20%

发文量

3130

审稿时长

122 days

期刊介绍： Food Chemistry publishes original research papers dealing with the advancement of the chemistry and biochemistry of foods or the analytical methods/ approach used. All papers should focus on the novelty of the research carried out.