Joint association of sleep duration and depression with new-onset hearing loss: a national cohort study.

IF 4 2区农林科学 Q2 NUTRITION & DIETETICS

Frontiers in Nutrition Pub Date : 2025-03-14 eCollection Date: 2025-01-01 DOI:10.3389/fnut.2025.1528567

Fang Wang, Yu-Jun Xiong, Da-Ming Shao, Tian Lv, Shiqin Chen, Qian-Yuan Zhu

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引用次数: 0

Abstract

Background: Hearing loss, a global health burden, is closely associated with depression and sleep disorders. However, the combined effects of sleep duration and depression on hearing loss risk remain unclear.

Methods: Data from the China Health and Retirement Longitudinal Study (CHARLS) were analyzed, including 6,374 adults aged 45 and older. Cox proportional hazards models assessed the relationship between depression, sleep duration, and hearing loss. Mediation analysis explored the potential mediating roles of CESD-10 score and sleep duration on new-onset hearing loss. Subgroup analyses by age, sex, and BMI were also conducted.

Results: Over a 7-year follow-up, 1,422 participants developed hearing loss. Both short sleep duration and high CESD-10 scores were independently associated with increased risk of hearing loss. Participants with long sleep duration but depression had a hazards ratio (HR) of 1.59 (95% CI: 1.35, 1.87) for hearing loss. Mediation analysis showed that sleep duration mediated 10.1% of the association between CESD-10 score and hearing loss, while CESD-10 score mediated 70.8% of the relationship between sleep duration and hearing loss.

Conclusion: This study highlights the significant and interconnected roles of sleep duration and depression in the development of hearing loss. Interventions addressing both sleep and depression may offer more effective strategies for preventing and managing hearing loss.

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来源期刊

Frontiers in Nutrition Agricultural and Biological Sciences-Food Science

CiteScore

5.20

自引率

8.00%

发文量

2891

审稿时长

12 weeks

期刊介绍： No subject pertains more to human life than nutrition. The aim of Frontiers in Nutrition is to integrate major scientific disciplines in this vast field in order to address the most relevant and pertinent questions and developments. Our ambition is to create an integrated podium based on original research, clinical trials, and contemporary reviews to build a reputable knowledge forum in the domains of human health, dietary behaviors, agronomy & 21st century food science. Through the recognized open-access Frontiers platform we welcome manuscripts to our dedicated sections relating to different areas in the field of nutrition with a focus on human health. Specialty sections in Frontiers in Nutrition include, for example, Clinical Nutrition, Nutrition & Sustainable Diets, Nutrition and Food Science Technology, Nutrition Methodology, Sport & Exercise Nutrition, Food Chemistry, and Nutritional Immunology. Based on the publication of rigorous scientific research, we thrive to achieve a visible impact on the global nutrition agenda addressing the grand challenges of our time, including obesity, malnutrition, hunger, food waste, sustainability and consumer health.