The impact of armed conflict on global patterns of childhood cancer

Pamela Espinoza, Henry E Rice, Paul H Wise, Nickhill Bhakta, Alexandra Mueller, Taisiya Yakimkova, Lisa M Force, Emily R Smith, Asya Agulnik
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Abstract

Section snippets

Incidence of cancer and related mortality in children in conflict zones

Children living in countries with armed conflict account for an increasing proportion of global paediatric cancer deaths over the past 30 years. This pattern has resulted from both a growing number of children living in countries with conflict over time and higher cancer mortality rates in countries in conflict compared with countries not in conflict. During the past three decades, approximately half of the children (aged 0–19 years) around the world lived in countries experiencing armed

Great divergence in global childhood cancer mortality

Many countries have successfully reduced mortality rates over recent decades, leading to aspirational projections of a great convergence in mortality rates for children.10 However, we found that for children with cancer in conflict settings, there is a great divergence, with higher cancer mortality rates and an increasing proportion of global cancer deaths for children in countries with armed conflict compared with countries without conflict.11 Without urgent action, this trend suggests that as

Limitations

There are several limitations to this study. First, our analysis risks stability bias: most sampling data in conflict settings come from the more stable and accessible regions, and the least data from where there is poor access to information, which can lead to falsely lowered measured levels of the impact of conflict on health services.15 Second, missing data might have biased our findings. In our study, 17·6% of the countries had missing conflict data in 1990, although this represented only

Conclusion

Countries experiencing armed conflict account for a large and increasing proportion of all global cancer cases and deaths among children. Continued efforts to reduce paediatric cancer mortality worldwide must confront the complex challenges inherent in providing health services in areas of armed conflict. Reaching the 60% survival goal for all children with cancer globally as set forth by the GICC cannot be achieved without improving childhood cancer care in areas of armed conflict. To meet

Declaration of interests

We declare no competing interests.
武装冲突对全球儿童癌症模式的影响
冲突地区儿童的癌症发病率和相关死亡率过去30年来,生活在武装冲突国家的儿童在全球儿童癌症死亡人数中所占比例越来越大。造成这种情况的原因是,随着时间的推移,生活在冲突国家的儿童越来越多,而且冲突国家的癌症死亡率高于未发生冲突的国家。在过去的三十年中,全世界大约有一半的儿童(0-19岁)生活在经历武装冲突的国家。全球儿童癌症死亡率的巨大差异近几十年来,许多国家成功地降低了死亡率,导致了儿童死亡率的巨大趋同的理想预测然而,我们发现,对于在冲突环境中患癌症的儿童来说,存在很大的差异,与没有冲突的国家相比,武装冲突国家的癌症死亡率更高,全球癌症死亡儿童的比例也在增加如果不采取紧急行动,这一趋势表明:局限性:本研究有几个局限性。首先,我们的分析存在稳定性偏差的风险:冲突环境中的大多数抽样数据来自更稳定、更容易获得的地区,而来自信息获取渠道较差的地区的数据最少,这可能导致冲突对卫生服务影响的测量水平被错误地降低其次,缺失的数据可能会影响我们的发现。在我们的研究中,17.6%的国家缺少1990年的冲突数据,尽管这仅代表结论:经历武装冲突的国家在全球所有儿童癌症病例和死亡中所占的比例很大,而且还在不断增加。继续努力降低全世界儿童癌症死亡率,必须面对在武装冲突地区提供保健服务所固有的复杂挑战。如果不改善武装冲突地区的儿童癌症护理,就无法实现GICC规定的全球所有癌症儿童存活60%的目标。我们声明没有相互竞争的利益。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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