Pamela Espinoza, Henry E Rice, Paul H Wise, Nickhill Bhakta, Alexandra Mueller, Taisiya Yakimkova, Lisa M Force, Emily R Smith, Asya Agulnik
{"title":"The impact of armed conflict on global patterns of childhood cancer","authors":"Pamela Espinoza, Henry E Rice, Paul H Wise, Nickhill Bhakta, Alexandra Mueller, Taisiya Yakimkova, Lisa M Force, Emily R Smith, Asya Agulnik","doi":"10.1016/s1470-2045(24)00559-x","DOIUrl":null,"url":null,"abstract":"<h2>Section snippets</h2><section><section><section><h2>Incidence of cancer and related mortality in children in conflict zones</h2>Children living in countries with armed conflict account for an increasing proportion of global paediatric cancer deaths over the past 30 years. This pattern has resulted from both a growing number of children living in countries with conflict over time and higher cancer mortality rates in countries in conflict compared with countries not in conflict. During the past three decades, approximately half of the children (aged 0–19 years) around the world lived in countries experiencing armed</section></section></section><section><section><section><h2>Great divergence in global childhood cancer mortality</h2>Many countries have successfully reduced mortality rates over recent decades, leading to aspirational projections of a great convergence in mortality rates for children.<sup>10</sup> However, we found that for children with cancer in conflict settings, there is a great divergence, with higher cancer mortality rates and an increasing proportion of global cancer deaths for children in countries with armed conflict compared with countries without conflict.<sup>11</sup> Without urgent action, this trend suggests that as</section></section></section><section><section><h2>Limitations</h2>There are several limitations to this study. First, our analysis risks stability bias: most sampling data in conflict settings come from the more stable and accessible regions, and the least data from where there is poor access to information, which can lead to falsely lowered measured levels of the impact of conflict on health services.<sup>15</sup> Second, missing data might have biased our findings. In our study, 17·6% of the countries had missing conflict data in 1990, although this represented only</section></section><section><section><h2>Conclusion</h2>Countries experiencing armed conflict account for a large and increasing proportion of all global cancer cases and deaths among children. Continued efforts to reduce paediatric cancer mortality worldwide must confront the complex challenges inherent in providing health services in areas of armed conflict. Reaching the 60% survival goal for all children with cancer globally as set forth by the GICC cannot be achieved without improving childhood cancer care in areas of armed conflict. To meet</section></section><section><section><h2>Declaration of interests</h2>We declare no competing interests.</section></section>","PeriodicalId":22865,"journal":{"name":"The Lancet Oncology","volume":"16 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Lancet Oncology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/s1470-2045(24)00559-x","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Section snippets
Incidence of cancer and related mortality in children in conflict zones
Children living in countries with armed conflict account for an increasing proportion of global paediatric cancer deaths over the past 30 years. This pattern has resulted from both a growing number of children living in countries with conflict over time and higher cancer mortality rates in countries in conflict compared with countries not in conflict. During the past three decades, approximately half of the children (aged 0–19 years) around the world lived in countries experiencing armed
Great divergence in global childhood cancer mortality
Many countries have successfully reduced mortality rates over recent decades, leading to aspirational projections of a great convergence in mortality rates for children.10 However, we found that for children with cancer in conflict settings, there is a great divergence, with higher cancer mortality rates and an increasing proportion of global cancer deaths for children in countries with armed conflict compared with countries without conflict.11 Without urgent action, this trend suggests that as
Limitations
There are several limitations to this study. First, our analysis risks stability bias: most sampling data in conflict settings come from the more stable and accessible regions, and the least data from where there is poor access to information, which can lead to falsely lowered measured levels of the impact of conflict on health services.15 Second, missing data might have biased our findings. In our study, 17·6% of the countries had missing conflict data in 1990, although this represented only
Conclusion
Countries experiencing armed conflict account for a large and increasing proportion of all global cancer cases and deaths among children. Continued efforts to reduce paediatric cancer mortality worldwide must confront the complex challenges inherent in providing health services in areas of armed conflict. Reaching the 60% survival goal for all children with cancer globally as set forth by the GICC cannot be achieved without improving childhood cancer care in areas of armed conflict. To meet