The Lancet Oncology

Salvage metastasis-directed therapy versus elective nodal radiotherapy for oligorecurrent nodal prostate cancer metastases (PEACE V–STORM): a phase 2, open-label, randomised controlled trial

Pub Date : 2025-05-05 DOI: 10.1016/s1470-2045(25)00197-4 Piet Ost, Shankar Siva, Sigmund Brabrand, Piet Dirix, Nick Liefhooghe, François-Xavier Otte, Alfonso Gomez-Iturriaga, Wouter Everaerts, Mohamed Shelan, Antonio Conde-Moreno, Fernando López Campos, Alexandros Papachristofilou, Matthias Guckenberger, Marta Scorsetti, Almudena Zapatero, Ana-Elena Villafranca Iturre, Clara Eito, Felipe Couñago, Paolo Muto, Wim Duthoy, Thomas Zilli

Targeted treatment of oligorecurrent prostate cancer?

Pub Date : 2025-05-05 DOI: 10.1016/s1470-2045(25)00215-3 Fabian Falkenbach, Tobias Maurer

Zanidatamab plus palbociclib and fulvestrant in previously treated patients with hormone receptor-positive, HER2-positive metastatic breast cancer: primary results from a two-part, multicentre, single-arm, phase 2a study

Pub Date : 2025-05-05 DOI: 10.1016/s1470-2045(25)00140-8 Santiago Escrivá-de-Romani, Juan M Cejalvo, Emilio Alba, Jennifer Friedmann, Álvaro Rodríguez-Lescure, Marie-France Savard, Rossanna C Pezo, Maria Gion, Manuel Ruiz-Borrego, Erika Hamilton, Timothy Pluard, Marc Webster, Muralidhar Beeram, Hannah Linden, Cristina Saura, Diana Shpektor, Bob Salim, Phoebe Harvey, Sara A Hurvitz