Noor Al-Zanoon, Jacqueline Cummine, Caroline C Jeffery, Daniel Aalto
{"title":"Compensatory behaviours after oral cancer: stretch reflex improves simulated tongue protrusion.","authors":"Noor Al-Zanoon, Jacqueline Cummine, Caroline C Jeffery, Daniel Aalto","doi":"10.1080/10255842.2025.2482128","DOIUrl":null,"url":null,"abstract":"<p><p>The study investigates if a simple stretch reflex mechanism can restore function in a biomechanical tongue model altered by fibrosis, a side effect of radiation therapy for head and neck cancers. Lateral deviation during tongue protrusion was reduced by 57.7% in a high fibrosis case and by 25.97% in a low fibrosis case. Muscle length analysis indicated recovery was driven by the lesion side genioglossus anterior and medial. The results suggest that adaptation may include stretch reflex and other mechanisms to restore function. The study's method establishes a foundation for future systematic investigation of motor adaptation in clinical populations.</p>","PeriodicalId":50640,"journal":{"name":"Computer Methods in Biomechanics and Biomedical Engineering","volume":" ","pages":"1-11"},"PeriodicalIF":1.7000,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Computer Methods in Biomechanics and Biomedical Engineering","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1080/10255842.2025.2482128","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS","Score":null,"Total":0}
引用次数: 0
Abstract
The study investigates if a simple stretch reflex mechanism can restore function in a biomechanical tongue model altered by fibrosis, a side effect of radiation therapy for head and neck cancers. Lateral deviation during tongue protrusion was reduced by 57.7% in a high fibrosis case and by 25.97% in a low fibrosis case. Muscle length analysis indicated recovery was driven by the lesion side genioglossus anterior and medial. The results suggest that adaptation may include stretch reflex and other mechanisms to restore function. The study's method establishes a foundation for future systematic investigation of motor adaptation in clinical populations.
期刊介绍:
The primary aims of Computer Methods in Biomechanics and Biomedical Engineering are to provide a means of communicating the advances being made in the areas of biomechanics and biomedical engineering and to stimulate interest in the continually emerging computer based technologies which are being applied in these multidisciplinary subjects. Computer Methods in Biomechanics and Biomedical Engineering will also provide a focus for the importance of integrating the disciplines of engineering with medical technology and clinical expertise. Such integration will have a major impact on health care in the future.