Can Adolescents Value the EQ-5D-Y-5L and EQ-5D-5L, and How Do the Values Compare? A Feasibility Study

IF 4.9 2区医学 Q1 ECONOMICS

Value in Health Pub Date : 2025-06-01 DOI:10.1016/j.jval.2025.02.013

Trudy A. Sullivan PhD , Emma H. Wyeth PhD , Robin M. Turner PhD , Paul Hansen PhD , Franz Ombler PhD , Nancy J. Devlin PhD , Sarah Derrett PhD

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引用次数: 0

Abstract

Objectives

Research into methods for eliciting adolescents’ health state preferences has mostly avoided tasks for identifying health states worse than dead, which is required for calculating quality-adjusted life years for economic evaluations. This study investigated the feasibility of eliciting the health state preferences of older adolescents, including for states worse than dead, using the EQ-5D-Y-5L (Y-5L) and EQ-5D-5L (5L), and compared participants’ preferences across the 2 instruments.

Methods

Two online surveys were created for the Y-5L and 5L, respectively, using the Potentially All Pairwise Rankings of all Possible Alternatives method, a type of adaptive discrete choice experiment, and a binary search algorithm for identifying health states worse than dead. The surveys were completed by 24 adolescents aged 16 to 19 years in 2 think-aloud sessions, with semistructured interviews at the end of each session. Dimension preference weights and rankings for the Y-5L and 5L were compared using intraclass correlation coefficients, Bland-Altman plots, and paired t tests.

Results

The adolescents were capable of valuing health states and identifying states worse than dead. There is no evidence of a difference in mean preference weights between the Y-5L and 5L, and the rankings of dimensions are similar.

Conclusions

Eliciting the health state preferences of older adolescents, including for states worse than dead, is feasible and acceptable. The similarity in Y-5L and 5L mean preference weights suggests that their corresponding value sets, if obtained using the methods used in this study, would be similar. Data quality was enhanced by the surveys being administered in a supportive environment.

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青少年是否会重视EQ-5D-Y-5L和EQ-5D-5L，两者的价值如何比较？可行性研究。

目的：对引发青少年健康状态偏好的方法的研究大多避免了确定比死亡更糟糕的健康状态的任务，这是计算经济评估的质量调整生命年所必需的。本研究探讨了使用EQ-5D-Y-5L （Y-5L）和EQ-5D-5L （5L）来引出大龄青少年健康状态偏好的可行性，包括对比死亡更糟糕的状态的偏好，并比较了两种工具中参与者的偏好。方法：分别对Y-5L和5L进行了两次在线调查，使用了所有可能选择的潜在全部成对排名（PAPRIKA）方法，一种自适应离散选择实验，以及用于识别比死亡更糟糕的健康状态的二分搜索算法。调查由24名年龄在16-19岁的青少年完成，他们分两期进行思考，每期结束时进行半结构化访谈。采用类内相关系数、Bland-Altman图和配对t检验比较Y-5L和5L的维度偏好权重和排名。结果：青少年能够评价健康状态和识别比死亡更糟糕的状态。没有证据表明在Y-5L和5L之间的平均偏好权重有差异，而且维度的排名是相似的。结论：询问大龄青少年的健康状态偏好，包括对比死亡更糟糕的状态的偏好，是可行和可接受的。Y-5L和5L平均偏好权重的相似性表明，如果使用本研究中使用的方法获得它们对应的值集，则它们将是相似的。在支助性环境中进行的调查提高了数据质量。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Value in Health 医学-卫生保健

CiteScore

6.90

自引率

6.70%

发文量

3064

审稿时长

3-8 weeks

期刊介绍： Value in Health contains original research articles for pharmacoeconomics, health economics, and outcomes research (clinical, economic, and patient-reported outcomes/preference-based research), as well as conceptual and health policy articles that provide valuable information for health care decision-makers as well as the research community. As the official journal of ISPOR, Value in Health provides a forum for researchers, as well as health care decision-makers to translate outcomes research into health care decisions.