Impaction of third molars and localized cancer of the oral cavity: A simple occasional finding? A retrospective case series and literature review.

IF 2.2 3区医学 Q2 Dentistry

Journal of Stomatology Oral and Maxillofacial Surgery Pub Date : 2025-03-03 DOI:10.1016/j.jormas.2025.102307

Matteo Zotti, Rossana Bussani, Michele Maglione

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引用次数: 0

Abstract

Objectives: The aim of this study is to analyze, through a literature review and the description of four clinical cases, whether prolonged tooth impaction may represent a trigger for the onset of oral carcinoma.

Materials e methods: In this report, four cases of patients needing the extraction of third molars in complete mucosal or bone impaction are described, which, due to the presence of an unusual radiographic and/or clinical aspect, were found to represent cases of oral carcinomas on histologic analysis. Patients were then referred to the ENT department for further care. A review of the literature has been performed as well.

Results: Literature analysis revealed the presence of only few case reports on the topic, suggesting therefore a lack of evidence on the correlation between tooth impaction and the onset of oral carcinomas.

Conclusions: Further studies are needed in order to give valid hypotheses. The concept of inflammation, that is at the base of oral carcinogenesis mechanism and tooth-related pathologies, such as pericoronitis, may be a common substrate to link these two phenomena.

Clinical relevance: A thorough analysis of the radiographic and clinical signs is strongly recommended prior and during surgical procedures, such as tooth extraction.

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第三磨牙嵌塞和局部口腔癌：一个简单的偶然发现？回顾性病例系列和文献综述。

目的：本研究的目的是通过文献回顾和对四个临床病例的描述，分析长期牙嵌塞是否可能是口腔癌发病的诱因。材料方法：在本报告中，我们描述了4例由于完全粘膜或骨嵌塞而需要拔除第三磨牙的患者，由于不寻常的影像学和/或临床方面的存在，在组织学分析中发现这是口腔癌的病例。患者随后被转到耳鼻喉科接受进一步治疗。对相关文献也进行了综述。结果：文献分析显示，关于该主题的病例报告很少，因此缺乏证据表明牙齿嵌塞与口腔癌发病之间的相关性。结论：为了给出有效的假设，需要进一步的研究。炎症的概念是口腔癌发生机制和牙齿相关病理（如冠周炎）的基础，可能是将这两种现象联系起来的共同基础。临床相关性：强烈建议在手术（如拔牙）之前和手术过程中对影像学和临床体征进行彻底分析。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Stomatology Oral and Maxillofacial Surgery Dentistry-Oral Surgery

CiteScore

2.20

自引率

9.10%

发文量

305

期刊介绍： J Stomatol Oral Maxillofac Surg publishes research papers and techniques - (guest) editorials, original articles, reviews, technical notes, case reports, images, letters to the editor, guidelines - dedicated to enhancing surgical expertise in all fields relevant to oral and maxillofacial surgery: from plastic and reconstructive surgery of the face, oral surgery and medicine, … to dentofacial and maxillofacial orthopedics. Original articles include clinical or laboratory investigations and clinical or equipment reports. Reviews include narrative reviews, systematic reviews and meta-analyses. All manuscripts submitted to the journal are subjected to peer review by international experts, and must: Be written in excellent English, clear and easy to understand, precise and concise; Bring new, interesting, valid information - and improve clinical care or guide future research; Be solely the work of the author(s) stated; Not have been previously published elsewhere and not be under consideration by another journal; Be in accordance with the journal''s Guide for Authors'' instructions: manuscripts that fail to comply with these rules may be returned to the authors without being reviewed. Under no circumstances does the journal guarantee publication before the editorial board makes its final decision. The journal is indexed in the main international databases and is accessible worldwide through the ScienceDirect and ClinicalKey Platforms.