Umair Arif, Chunxia Zhang, Muhammad Waqas Chaudhary, Sajid Hussain
{"title":"An Adaptive Dendritic Neural Model for Lung Cancer Prediction.","authors":"Umair Arif, Chunxia Zhang, Muhammad Waqas Chaudhary, Sajid Hussain","doi":"10.1080/10255842.2025.2472013","DOIUrl":null,"url":null,"abstract":"<p><p>Lung cancer is a leading cause of cancer-related deaths, often diagnosed late due to its aggressive nature. This study presents a novel Adaptive Dendritic Neural Model (ADNM) to enhance diagnostic accuracy in high-dimensional healthcare data. Utilizing hyperparameter optimization and activation mechanisms, ADNM improves scalability and feature selection for multi-class lung cancer prediction. Using a Kaggle dataset, Particle Swarm Optimization (PSO) selected features, while bootstrap assessed performance. ADNM achieved 98.39% accuracy, 99% AUC, and a Cohen's kappa of 96.95%, with rapid convergence via the Adam optimizer, demonstrating its potential for improving early diagnosis and personalized treatment in oncology.</p>","PeriodicalId":50640,"journal":{"name":"Computer Methods in Biomechanics and Biomedical Engineering","volume":" ","pages":"1-14"},"PeriodicalIF":1.7000,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Computer Methods in Biomechanics and Biomedical Engineering","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1080/10255842.2025.2472013","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS","Score":null,"Total":0}
引用次数: 0
Abstract
Lung cancer is a leading cause of cancer-related deaths, often diagnosed late due to its aggressive nature. This study presents a novel Adaptive Dendritic Neural Model (ADNM) to enhance diagnostic accuracy in high-dimensional healthcare data. Utilizing hyperparameter optimization and activation mechanisms, ADNM improves scalability and feature selection for multi-class lung cancer prediction. Using a Kaggle dataset, Particle Swarm Optimization (PSO) selected features, while bootstrap assessed performance. ADNM achieved 98.39% accuracy, 99% AUC, and a Cohen's kappa of 96.95%, with rapid convergence via the Adam optimizer, demonstrating its potential for improving early diagnosis and personalized treatment in oncology.
期刊介绍:
The primary aims of Computer Methods in Biomechanics and Biomedical Engineering are to provide a means of communicating the advances being made in the areas of biomechanics and biomedical engineering and to stimulate interest in the continually emerging computer based technologies which are being applied in these multidisciplinary subjects. Computer Methods in Biomechanics and Biomedical Engineering will also provide a focus for the importance of integrating the disciplines of engineering with medical technology and clinical expertise. Such integration will have a major impact on health care in the future.