{"title":"Mycochemistry, Traditional Uses, and Nutraceutical Potential of Laricifomes officinalis: A Biotechnological and Pharmacological Perspective.","authors":"Yusufjon Gafforov, Milena Rašeta, Oksana Mykchaylova, Sylvie Rapior, Maja Karaman, Jovana Mišković, Şule İnci, Manzura Yarasheva, Arshad Mehmood Abbasi, Soumya Ghosh","doi":"10.1007/s11130-025-01316-9","DOIUrl":null,"url":null,"abstract":"<p><p>Laricifomes officinalis is a medicinal wood-inhabiting fungus renowned for its health benefits, particularly in traditional European medicine for the prevention and treatment of pulmonary conditions such as asthma, pneumonia, and tuberculosis. Beyond its therapeutic applications, L. officinalis plays an important ecological role by contributing to nutrient cycling in forest ecosystems. This review provides a comprehensive analysis of the current literature on L. officinalis, focusing on its phytochemical composition, traditional uses, pharmacological potential, and conservation status. The species is a rich source of bioactive compounds, including coumarin derivatives, indole compounds, phenolic compounds, polysaccharides, terpenoids and sterols, which exhibit a wide array of biological activities, such as antibacterial, anticancer, antifungal, anti-inflammatory, antioxidant, and antiviral effects. Drawing on extensive searches in scientific databases including Google Scholar, PubMed, Scopus, and Web of Science, this review examines the distribution, ecological significance, taxonomy, and pharmacological applications of L. officinalis. Given the growing threats of overexploitation and habitat loss, the conservation of L. officinalis is crucial. This review discusses various sustainable cultivation strategies, including establishing culture collections and regulating biosynthetic activity through LED and laser light techniques, show potential for preserving and enhancing the production of its bioactive compounds. Despite recent advances, further research is required to better understand the pharmacological efficacy and safety of L. officinalis, thereby unlocking its full medicinal potential for future therapeutic applications. This review underscores the necessity of integrating ecological conservation with pharmaceutical research, highlighting the dual importance of L. officinalis in natural ecosystems and therapeutic applications.</p>","PeriodicalId":20092,"journal":{"name":"Plant Foods for Human Nutrition","volume":"80 1","pages":"77"},"PeriodicalIF":3.1000,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Plant Foods for Human Nutrition","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.1007/s11130-025-01316-9","RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CHEMISTRY, APPLIED","Score":null,"Total":0}
引用次数: 0
Abstract
Laricifomes officinalis is a medicinal wood-inhabiting fungus renowned for its health benefits, particularly in traditional European medicine for the prevention and treatment of pulmonary conditions such as asthma, pneumonia, and tuberculosis. Beyond its therapeutic applications, L. officinalis plays an important ecological role by contributing to nutrient cycling in forest ecosystems. This review provides a comprehensive analysis of the current literature on L. officinalis, focusing on its phytochemical composition, traditional uses, pharmacological potential, and conservation status. The species is a rich source of bioactive compounds, including coumarin derivatives, indole compounds, phenolic compounds, polysaccharides, terpenoids and sterols, which exhibit a wide array of biological activities, such as antibacterial, anticancer, antifungal, anti-inflammatory, antioxidant, and antiviral effects. Drawing on extensive searches in scientific databases including Google Scholar, PubMed, Scopus, and Web of Science, this review examines the distribution, ecological significance, taxonomy, and pharmacological applications of L. officinalis. Given the growing threats of overexploitation and habitat loss, the conservation of L. officinalis is crucial. This review discusses various sustainable cultivation strategies, including establishing culture collections and regulating biosynthetic activity through LED and laser light techniques, show potential for preserving and enhancing the production of its bioactive compounds. Despite recent advances, further research is required to better understand the pharmacological efficacy and safety of L. officinalis, thereby unlocking its full medicinal potential for future therapeutic applications. This review underscores the necessity of integrating ecological conservation with pharmaceutical research, highlighting the dual importance of L. officinalis in natural ecosystems and therapeutic applications.
落叶松（Laricifomes officinalis）是一种药用木栖真菌，以其健康益处而闻名，特别是在传统的欧洲医学中，用于预防和治疗哮喘、肺炎和结核病等肺部疾病。除治疗用途外，马蹄草还通过促进森林生态系统的养分循环发挥重要的生态作用。本文对马蹄草的植物化学成分、传统用途、药理潜力和保护现状进行了综述。该植物含有丰富的生物活性化合物，包括香豆素衍生物、吲哚化合物、酚类化合物、多糖、萜类和甾醇，具有广泛的生物活性，如抗菌、抗癌、抗真菌、抗炎、抗氧化和抗病毒作用。通过对谷歌Scholar、PubMed、Scopus和Web of Science等科学数据库的广泛检索，本文综述了L. officinalis的分布、生态意义、分类和药理应用。鉴于过度开发和栖息地丧失的威胁日益严重，对石斛的保护至关重要。本文综述了各种可持续培养策略，包括建立培养物和通过LED和激光技术调节生物合成活性，显示了保存和提高其生物活性化合物生产的潜力。尽管最近取得了一些进展，但还需要进一步的研究来更好地了解马蹄草的药理功效和安全性，从而释放其在未来治疗应用中的全部药用潜力。本文强调了将生态保护与药物研究结合起来的必要性，强调了马粪草在自然生态系统和治疗应用中的双重重要性。
期刊介绍：
Plant Foods for Human Nutrition (previously Qualitas Plantarum) is an international journal that publishes reports of original research and critical reviews concerned with the improvement and evaluation of the nutritional quality of plant foods for humans, as they are influenced by:
- Biotechnology (all fields, including molecular biology and genetic engineering)
- Food science and technology
- Functional, nutraceutical or pharma foods
- Other nutrients and non-nutrients inherent in plant foods
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
