Rapid estrogen signaling drives binge drinking.

IF 14.6 1区医学 Q1 NEUROSCIENCES

Trends in Neurosciences Pub Date : 2025-02-20 DOI:10.1016/j.tins.2025.02.001

Xavier J Maddern, Lauren T Ursich, Leigh C Walker

引用次数: 0

Abstract

Sex hormones shape behavior through diverse mechanisms. In a recent study, Zallar et al. have uncovered a rapid, nongenomic estrogen signaling pathway mediating binge drinking in female mice via membrane-associated estrogen receptor α (ERα) in the bed nucleus of the stria terminalis (BNST). These findings reveal sex-specific neurobiological underpinnings of alcohol use linked to naturally circulating hormone levels.

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来源期刊

Trends in Neurosciences 医学-神经科学

CiteScore

26.50

自引率

1.30%

发文量

123

审稿时长

6-12 weeks

期刊介绍： For over four decades, Trends in Neurosciences (TINS) has been a prominent source of inspiring reviews and commentaries across all disciplines of neuroscience. TINS is a monthly, peer-reviewed journal, and its articles are curated by the Editor and authored by leading researchers in their respective fields. The journal communicates exciting advances in brain research, serves as a voice for the global neuroscience community, and highlights the contribution of neuroscientific research to medicine and society.