Enabling evolvability to evolve

IF 45.8 1区综合性期刊 Q1 MULTIDISCIPLINARY SCIENCES

Science Pub Date : 2025-02-20

Edo Kussell

引用次数: 0

Abstract

Evolvability, or the capacity to generate adaptive phenotypic variation, can itself evolve in response to selection (1). Species that evolve too slowly may be unable to adapt to environmental change and are more likely to go extinct than faster-evolving species. Yet what it takes to get evolvability to evolve, in nature or in the lab, has remained puzzling. For example, many generations might be needed for natural selection to change a species’ ability to adapt. Higher evolvability can result in lower heritability, a cornerstone of natural selection’s ability to act, and the same degree of evolvability might not suit all traits equally. On page 840 of this issue, Barnett et al. (2) describe how experimental evolution can yield increased evolvability by localized hypermutation in populations of bacteria exposed to an alternating selection regime, akin to the regularly fluctuating conditions that pathogenic bacteria experience moving from one host to another.

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使可进化性进化

可进化性，或产生适应性表型变异的能力，本身也可以随着选择而进化(1)。进化太慢的物种可能无法适应环境变化，比进化更快的物种更有可能灭绝。然而，无论在自然界还是在实验室中，究竟是什么让可进化性得以进化，仍然令人困惑。例如，自然选择可能需要许多代才能改变一个物种的适应能力。较高的可进化性可能导致较低的遗传性，而遗传性是自然选择能力的基石，同样程度的可进化性可能不适合所有特征。在这期杂志的840页，Barnett等人(2)描述了实验进化如何通过暴露于交替选择制度下的细菌群体的局部高突变来提高可进化性，类似于致病菌从一个宿主转移到另一个宿主所经历的有规律的波动条件。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Science 综合性期刊-综合性期刊

CiteScore

61.10

自引率

0.90%

发文量

审稿时长

2.1 months

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