Microfluidics as a promising technology for personalized medicine.

IF 2.2 4区工程技术 Q3 PHARMACOLOGY & PHARMACY

Bioimpacts Pub Date : 2024-06-16 eCollection Date: 2025-01-01 DOI:10.34172/bi.29944

Zahra Oushyani Roudsari, Zahra Esmaeili, Nafiseh Nasirzadeh, Saeed Heidari Keshel, Farshid Sefat, Hassan Bakhtyari, Samad Nadri

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引用次数: 0

Abstract

Introduction: Due to the recent advances in biomedicine and the increasing understanding of the molecular mechanism of diseases, healthcare approaches have tended towards preventive and personalized medicine. Consequently, in recent decades, the utilization of interdisciplinary technologies such as microfluidic systems had a significant increase to provide more accurate high throughput diagnostic/therapeutic methods.

Methods: In this article, we will review a summary of innovations in microfluidic technologies toward improving personalized biomolecular diagnostics, drug screening, and therapeutic strategies.

Results: Microfluidic systems by providing a controllable space for fluid flow, three-dimensional growth of cells, and miniaturization of molecular experiments are useful tools in the field of personalization of health and treatment. These conditions have enabled the potential to carry out studies like; disease modeling, drug screening, and improving the accuracy of diagnostic methods.

Conclusion: Microfluidic devices have become promising point-of-care (POC) and personalized medicine instruments due to their ability to perform diagnostic tests with small sample volumes, cost reduction, high resolution, and automation.

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微流体技术在个体化医疗中的应用前景广阔。

导读：由于近年来生物医学的进步和对疾病分子机制的不断了解，医疗保健方法趋向于预防和个性化医疗。因此，近几十年来，跨学科技术（如微流体系统）的应用显著增加，以提供更准确的高通量诊断/治疗方法。方法：在本文中，我们将回顾微流控技术在提高个性化生物分子诊断、药物筛选和治疗策略方面的创新。结果：微流控系统为流体流动、细胞三维生长和分子实验的小型化提供了可控制的空间，是个性化健康和治疗领域的有用工具。这些条件有可能进行研究，如；疾病建模，药物筛选，提高诊断方法的准确性。结论：微流控设备由于能够以小样本量、低成本、高分辨率和自动化进行诊断测试，已成为有前途的医疗点（POC）和个性化医疗仪器。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Bioimpacts Pharmacology, Toxicology and Pharmaceutics-Pharmaceutical Science

CiteScore

4.80

自引率

7.70%

发文量

审稿时长

5 weeks

期刊介绍： BioImpacts (BI) is a peer-reviewed multidisciplinary international journal, covering original research articles, reviews, commentaries, hypotheses, methodologies, and visions/reflections dealing with all aspects of biological and biomedical researches at molecular, cellular, functional and translational dimensions.