Transformation of Cannabidiol (CBD) during its high-temperature extraction: Studies involving model systems, hemp and functional foods containing CBD

IF 8.5 1区农林科学 Q1 CHEMISTRY, APPLIED

Food Chemistry Pub Date : 2025-02-17 DOI:10.1016/j.foodchem.2025.143447

Rafal Typek, Michal P. Dybowski, Andrzej L. Dawidowicz

{"title":"Transformation of Cannabidiol (CBD) during its high-temperature extraction: Studies involving model systems, hemp and functional foods containing CBD","authors":"Rafal Typek, Michal P. Dybowski, Andrzej L. Dawidowicz","doi":"10.1016/j.foodchem.2025.143447","DOIUrl":null,"url":null,"abstract":"<div><div>Most approaches to plants and foodstuffs analysis involve the application of liquid extraction methods for the isolation of their components. The present paper shows and discusses the transformations that CBD may undergo during its high-temperature extraction with methanol, dichloromethane, ethyl acetate and hexane from hemp and CBD containing commercially available functional foods. According to the performed research, CBD can transform not only into cannabinoids, which are hemp metabolites (i.e. Δ8/Δ9-THC, CBN), but also into other previously unknown derivatives, the number and quantity of which depend on the type of the extrahent and the oxygen content in the extraction system. In the case of each solvent used, the CBD transformation degree is strongly affected by the humidity of the extracted hemp. The results presented in this work are important both for hemp analysis, including the research dealing with hemp metabolism, but also for functional food containing CBD.</div></div>","PeriodicalId":318,"journal":{"name":"Food Chemistry","volume":"476 ","pages":"Article 143447"},"PeriodicalIF":8.5000,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Food Chemistry","FirstCategoryId":"97","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0308814625006983","RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, APPLIED","Score":null,"Total":0}

引用次数: 0

Abstract

Most approaches to plants and foodstuffs analysis involve the application of liquid extraction methods for the isolation of their components. The present paper shows and discusses the transformations that CBD may undergo during its high-temperature extraction with methanol, dichloromethane, ethyl acetate and hexane from hemp and CBD containing commercially available functional foods. According to the performed research, CBD can transform not only into cannabinoids, which are hemp metabolites (i.e. Δ8/Δ9-THC, CBN), but also into other previously unknown derivatives, the number and quantity of which depend on the type of the extrahent and the oxygen content in the extraction system. In the case of each solvent used, the CBD transformation degree is strongly affected by the humidity of the extracted hemp. The results presented in this work are important both for hemp analysis, including the research dealing with hemp metabolism, but also for functional food containing CBD.

Abstract Image

查看原文本刊更多论文

求助全文

约1分钟内获得全文求助全文

来源期刊

Food Chemistry 工程技术-食品科技

CiteScore

16.30

自引率

10.20%

发文量

3130

审稿时长

122 days

期刊介绍： Food Chemistry publishes original research papers dealing with the advancement of the chemistry and biochemistry of foods or the analytical methods/ approach used. All papers should focus on the novelty of the research carried out.