Prescripción prolongada de antidepresivos en atención primaria. Impacto en la salud pública

IF 1.8 4区医学 Q2 MEDICINE, GENERAL & INTERNAL

Atencion Primaria Pub Date : 2025-02-12 DOI:10.1016/j.aprim.2025.103234

Antonio José Madueño-Caro , Gonzalo Berro-Ramírez , Luis Chávez-Gata , Rubén Torrescusa-Camisón , José Antonio Climent-Rodríguez , Yolanda Navarro-Abal , Juan Gómez-Salgado

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引用次数: 0

Abstract

Objective

To determine the variables associated with the prescription of long-term antidepressants (more than three years) to patients in a primary health area.

Design

Descriptive observational study.

Site

Basic health area of primary care.

Participants

A sample of 315 participants assigned to a basic health area, who have been prescribed at least one antidepressant during a calendar year.

Interventions

Institutional information sources.

Main measurements

Those variables that can be associated with a prolonged prescription of antidepressants. The selection of the patients was carried out by simple random sampling. Analysis using Chi-Square contrast for the comparison of proportions. Multivariate binary logistic regression to observe possible associations in the set of variables.

Results

The study analyzed a majority of women (75.2%) with a mean age of 61.7 years (SD = 38.18). SSRIs (Selective Serotonin Reuptake Inhibitors) were the most commonly used antidepressants (50.5%), especially sertraline. Dysthymia was the main diagnosis (17%). Prolonged duration of treatment was associated with SSRIs and dysthymia. Logistic regression showed relevant factors: dysthymia, age, number of antidepressants, and SSRI use.

Conclusion

There is a high prevalence of prescription beyond three years. It is observed how dysthymic disorder is associated with a prolonged duration of treatment, as well as age, SSRI use, antidepressant change, and the total number of antidepressants prescribed.

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在初级保健中长期服用抗抑郁药。对公共卫生的影响

目的了解某基层卫生保健地区患者长期服用抗抑郁药（3年以上）的相关因素。设计描述性观察性研究。site初级保健的基本保健领域。参与者分配到一个基本卫生区域的315名参与者的样本，他们在一个日历年内至少服用过一种抗抑郁药。机构信息来源。主要测量指标那些与长期服用抗抑郁药有关的变量。患者的选择采用简单随机抽样的方法。采用卡方对比进行比例比较分析。多元二元逻辑回归，以观察在一组变量中可能存在的关联。结果研究分析了大多数女性（75.2%），平均年龄为61.7岁（SD = 38.18）。SSRIs（选择性血清素再摄取抑制剂）是最常用的抗抑郁药（50.5%），尤其是舍曲林。心境恶劣是主要诊断（17%）。延长治疗时间与SSRIs和心境恶劣有关。Logistic回归显示相关因素：心境恶劣、年龄、抗抑郁药物数量和SSRI的使用。结论3年以上处方率较高。观察到心境恶劣障碍与治疗持续时间延长、年龄、SSRI使用、抗抑郁药改变和抗抑郁药处方总数的关系。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Atencion Primaria 医学-医学：内科

CiteScore

2.90

自引率

8.00%

发文量

156

审稿时长

33 days

期刊介绍： Atención Primaria es una revista que publica trabajos de investigación relativos al ámbito de la atención primaria de salud. Desde el punto de vista conceptual, Atención Primaria asume el nuevo modelo de atención primaria de salud, orientado no sólo a la curación de la enfermedad, sino también a su prevención y a la promoción de la salud, tanto en el plano individual como en el de la familia y la comunidad. En estos nuevos aspectos que definen el modelo de atención primaria de salud es en los que se centran los trabajos de investigación que publica Atención Primaria, la primera revista de originales española creada para recoger y difundir la producción científica realizada desde los centros de atención primaria de salud sobre cuestiones como protocolización de la asistencia, programas de prevención, seguimiento y control de pacientes crónicos, organización y gestión de la asistencia primaria, entre otros.