In vitro gastrointestinal digestion of phlorotannins from Ulva lactuca: Nutritional value and implications in disease mechanisms through pharmacology network

IF 7 1区农林科学 Q1 FOOD SCIENCE & TECHNOLOGY

Food Research International Pub Date : 2025-02-04 DOI:10.1016/j.foodres.2025.115928

Francia G. López-Cárdenas , Raquel Mateos , Jorge A. Sánchez-Burgos , Víctor M. Zamora-Gasga , Francisco J. Blancas-Benítez , Aaron F. González-Cordova , Sonia G. Sáyago-Ayerdi

引用次数: 0

Abstract

Ulva lactuca, a green marine macroalga, is known for its potential health benefits due to bioactive compounds such as phlorotannins (PhT). This study aimed to identify and characterize the PhT profile in Ulva lactuca, evaluate their bioaccessibility, and explore their potential therapeutic targets through pharmacological network analysis. The study identified twenty PhT, showing a bioaccessibility of 54 %. Pharmacological network analysis revealed 54 potential targets associated with various disease pathways, including cancer. The findings highlight the nutritional value of Ulva lactuca and suggest the therapeutic potential of its PhT, offering new insights for future research and health applications.

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来源期刊

Food Research International 工程技术-食品科技

CiteScore

12.50

自引率

7.40%

发文量

1183

审稿时长

79 days

期刊介绍： Food Research International serves as a rapid dissemination platform for significant and impactful research in food science, technology, engineering, and nutrition. The journal focuses on publishing novel, high-quality, and high-impact review papers, original research papers, and letters to the editors across various disciplines in the science and technology of food. Additionally, it follows a policy of publishing special issues on topical and emergent subjects in food research or related areas. Selected, peer-reviewed papers from scientific meetings, workshops, and conferences on the science, technology, and engineering of foods are also featured in special issues.