Pengkun Guo , Wen Gao , Riqiang Lin , Xiatian Wang , Jiale Lan , Jiaming Zhang , Yanan Wang , Lin Zhu , Yongcheng Zhang , Feng Li , Weijie Zheng , Tianlong Zhao , Kwok-Ho Lam , Xiaojing Gong , Zhihua Xie , Yalin Qin , Shujun Zhang
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引用次数: 0
Abstract
Dual-mode imaging combining photoacoustic and ultrasound modalities holds great promise for comprehensive tissue characterization. In traditional dual-mode imaging systems, however, the opaque ultrasound transducers are integrated in complex optical and ultrasound paths, leading to compromises in imaging efficiency and sensitivity. To address these challenges, we design and produce highly transparent Pb(Mg,Nb)O3PbTiO3 ceramics with exceptional transparency of 68%, alongside a remarkable ultrahigh piezoelectric d33 of 1500 pC/N. Leveraging this material, we fabricate a high-sensitivity transparent piezoelectric ultrasound transducer (TPUT) with a center frequency of 16 MHz and a bandwidth of 30%, which seamlessly integrating ultrasound and photoacoustic capabilities into one system to achieve simultaneous photoacoustic/ultrasound dual-mode imaging, showcasing a remarkable sensitivity for deep-tissue detection (e.g., 7.5 mm thick chicken breast meat). Additionally, invivo photoacoustic imaging of subcutaneous microvasculature in a mouse ear was successfully achieved via 28 MHz TPUT. Our innovation not only advances imaging performance but also offers a cost-effective solution, paving the way for transformative biomedical imaging applications.
期刊介绍:
The Journal of Materiomics is a peer-reviewed open-access journal that aims to serve as a forum for the continuous dissemination of research within the field of materials science. It particularly emphasizes systematic studies on the relationships between composition, processing, structure, property, and performance of advanced materials. The journal is supported by the Chinese Ceramic Society and is indexed in SCIE and Scopus. It is commonly referred to as J Materiomics.