Potentially harmful effects of micro-/nanoplastics on humans as well as protective actions of dietary natural products

IF 15.1 1区农林科学 Q1 FOOD SCIENCE & TECHNOLOGY

Trends in Food Science & Technology Pub Date : 2025-02-01 DOI:10.1016/j.tifs.2024.104841

Jin Cheng , Jiahui Li , Ruo-Gu Xiong , Dan-Dan Zhou , Si-Yu Huang , Si-Xia Wu , Ao Shang , Guo-Yi Tang , Hua-Bin Li , Ren-You Gan

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引用次数: 0

Abstract

Background

Microplastics and nanoplastics are hot research topics in many fields (e.g., food science, nutrition, environment, ecology and toxicology). They have potentially harmful effects on humans, such as neurotoxicity, carcinogenicity and reproductive toxicity. Humans are exposed to microplastics and nanoplastics through food, drinking water and air. Thus, it is necessary to discover dietary natural products that can protect against these harmful effects caused by microplastics and nanoplastics.

Scope and approach

This review summarizes potentially harmful effects and underlying mechanisms of microplastics and nanoplastics on humans, according to high-quality literature from Web of Science and PubMed databases. Furthermore, dietary natural products that can protect humans against these harmful effects are also summarized and discussed.

Key findings and conclusions

Microplastics and nanoplastics have been detected in many organs of humans, such as the colon, placenta, and heart. Epidemiological studies indicate that microplastics are positively associated with colorectal cancer, myocardial infarction, stroke, and even death. Experimental studies demonstrate that microplastics and nanoplastics have carcinogenicity, neurotoxicity, reproductive toxicity, development toxicity, hepatoxicity, as well as nephrotoxicity, and can induce intestinal dysfunction, diabetes, obesity and cardiovascular diseases. On the other hand, some dietary natural products, such as probiotics, chrysoeriol, salidroside, resveratrol, herbacetin, melatonin, quercetin, and vitamin D, can ameliorate toxicities induced by microplastics and nanoplastics. In the future, priorities should be implemented to discover more dietary natural products that can protect humans from the toxicities of microplastics and nanoplastics. Overall, we hope that this review can attract more attention to the harmful effects of microplastics and nanoplastics and also highlight the potential protective actions of dietary natural products against them.

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来源期刊

Trends in Food Science & Technology 工程技术-食品科技

CiteScore

32.50

自引率

2.60%

发文量

322

审稿时长

37 days

期刊介绍： Trends in Food Science & Technology is a prestigious international journal that specializes in peer-reviewed articles covering the latest advancements in technology, food science, and human nutrition. It serves as a bridge between specialized primary journals and general trade magazines, providing readable and scientifically rigorous reviews and commentaries on current research developments and their potential applications in the food industry. Unlike traditional journals, Trends in Food Science & Technology does not publish original research papers. Instead, it focuses on critical and comprehensive reviews to offer valuable insights for professionals in the field. By bringing together cutting-edge research and industry applications, this journal plays a vital role in disseminating knowledge and facilitating advancements in the food science and technology sector.