Clinical Outcomes of the PAUL® Glaucoma Implant for secondary glaucoma after vitreoretinal surgery.

IF 2.1 4区医学 Q2 OPHTHALMOLOGY

Ophthalmologica Pub Date : 2025-01-24 DOI:10.1159/000543748

Constance Weber, Pascal Schipper, Wolfgang Walz, Kristin Raming, Sandrine Künzel, Frank G Holz, Raffael Liegl, Karl Mercieca

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引用次数: 0

Abstract

Background: To report clinical outcomes from a single-center cohort undergoing PAUL® Glaucoma Implant (PGI) surgery for secondary glaucoma after vitreoretinal surgery (VR).

Methods: Retrospective review of patients undergoing PGI surgery at the University Eye Hospital Bonn, Germany, from 04/2021 to 05/2023.

Results: 33 eyes of 33 patients were included. Mean number of preoperative VR surgeries was 2 (1-4), the majority following retinal detachment (23 eyes, 69.7%). 18 eyes had previous silicone oil tamponade (54.4%). Complete (without drops) and qualified (with or without drops) success rates (95% CI) after one year were 69.7% (54.5-84.8) and 97% (90.9-100) for Criterion A (IOP≤21mmHg), 66.7% (51.5-81.8) and 87.9% (51.5-81.8) for Criterion B (IOP≤18mmHg), 54.5% (39.4-72.7) and 72.7% (54.5-87.9%) for Criterion C (IOP≤15mmHg) and 24.2% (9.1-39.4) and 30.3% (15.2-48.4) for Criterion D (IOP≤12mmHg) respectively. Mean IOP decreased from 25.64 mmHg (14-49 mmHg) to 13.59 mmHg (8-20 mmHg) (reduction of 41.1%) after 12 months with a reduction of IOP-lowering agents from 3.21 (1 - 5) to 0.38 (0 - 3). Seven eyes (21.2%) developed postoperative complications, most of which eventually resolved. Two eyes had a tube flushing because of high postoperative IOP with silicone oil obstruction. Postoperative non-glaucoma related procedures were performed in 10 eyes (24.4%). None of these led to high IOP or further complications in the postoperative phase.

Conclusions: PGI surgery is an effective procedure for reducing both IOP and topical therapy in patients with uncontrolled secondary glaucoma following vitreoretinal surgery. Non-glaucoma related procedures can be safely performed after PGI implantation with good IOP control.

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来源期刊

Ophthalmologica 医学-眼科学

CiteScore

5.10

自引率

3.80%

发文量

审稿时长

3 months

期刊介绍： Published since 1899, ''Ophthalmologica'' has become a frequently cited guide to international work in clinical and experimental ophthalmology. It contains a selection of patient-oriented contributions covering the etiology of eye diseases, diagnostic techniques, and advances in medical and surgical treatment. Straightforward, factual reporting provides both interesting and useful reading. In addition to original papers, ''Ophthalmologica'' features regularly timely reviews in an effort to keep the reader well informed and updated. The large international circulation of this journal reflects its importance.