Cocaine-induced Vasculitis: Uncommon Manifestations in the Lower Extremities - A Case Report.

IF 0.9 Q3 MEDICINE, GENERAL & INTERNAL
Israel Umoh, Elizabeth Mikhail, Mahmoud Ibrahim, Arvind Kunadi
{"title":"Cocaine-induced Vasculitis: Uncommon Manifestations in the Lower Extremities - A Case Report.","authors":"Israel Umoh, Elizabeth Mikhail, Mahmoud Ibrahim, Arvind Kunadi","doi":"10.55729/2000-9666.1441","DOIUrl":null,"url":null,"abstract":"<p><p>Levamisole-induced vasculitis is a recognized dermatopathologic phenomenon frequently observed in individuals engaged in illicit substance use, particularly cocaine. Levimasole's structural resemblance to cocaine leads to its utilization as a cutting or bulking agent, creating an illusion of unaltered purity. While this vasculitis typically manifests in cartilaginous areas such as the ears and nose, it can also occur, though less commonly, in the lower extremities. At the time of writing, our case is the 3<sup>rd</sup> case of levamisole induced vasculitis to affect the lower extremities. The primary therapeutic approach involves discontinuing the use of the implicated agent, as repeated exposure to levamisole tends to exacerbate skin lesions with subsequent use. In this report, we present the case of a 30-year-old female with a history of cocaine use, who presented with extensive bilateral chronic leg wounds affecting her ambulation. Histopathological analysis of the skin biopsy confirmed signs of levamisole-induced vasculitis. Our objective is to raise awareness among both the public and healthcare providers, emphasizing the consideration of cocaine-induced vasculitis in patients presenting with chronic non-healing wounds, even in less common anatomical regions. Encouraging substance use cessation is crucial in the management of such cases.</p>","PeriodicalId":15460,"journal":{"name":"Journal of Community Hospital Internal Medicine Perspectives","volume":"15 1","pages":"89-92"},"PeriodicalIF":0.9000,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11759085/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Community Hospital Internal Medicine Perspectives","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.55729/2000-9666.1441","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0

Abstract

Levamisole-induced vasculitis is a recognized dermatopathologic phenomenon frequently observed in individuals engaged in illicit substance use, particularly cocaine. Levimasole's structural resemblance to cocaine leads to its utilization as a cutting or bulking agent, creating an illusion of unaltered purity. While this vasculitis typically manifests in cartilaginous areas such as the ears and nose, it can also occur, though less commonly, in the lower extremities. At the time of writing, our case is the 3rd case of levamisole induced vasculitis to affect the lower extremities. The primary therapeutic approach involves discontinuing the use of the implicated agent, as repeated exposure to levamisole tends to exacerbate skin lesions with subsequent use. In this report, we present the case of a 30-year-old female with a history of cocaine use, who presented with extensive bilateral chronic leg wounds affecting her ambulation. Histopathological analysis of the skin biopsy confirmed signs of levamisole-induced vasculitis. Our objective is to raise awareness among both the public and healthcare providers, emphasizing the consideration of cocaine-induced vasculitis in patients presenting with chronic non-healing wounds, even in less common anatomical regions. Encouraging substance use cessation is crucial in the management of such cases.

求助全文
约1分钟内获得全文 求助全文
来源期刊
自引率
0.00%
发文量
106
审稿时长
17 weeks
期刊介绍: JCHIMP provides: up-to-date information in the field of Internal Medicine to community hospital medical professionals a platform for clinical faculty, residents, and medical students to publish research relevant to community hospital programs. Manuscripts that explore aspects of medicine at community hospitals welcome, including but not limited to: the best practices of community academic programs community hospital-based research opinion and insight from community hospital leadership and faculty the scholarly work of residents and medical students affiliated with community hospitals.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信