Effects of digital-based interventions on the outcomes of the eligibility criteria for sarcopenia in healthy older adults: A systematic review and meta-analysis

IF 12.5 1区医学 Q1 CELL BIOLOGY

Ageing Research Reviews Pub Date : 2025-02-01 DOI:10.1016/j.arr.2025.102663

Hyuma Makizako , Daijo Shiratsuchi , Shoma Akaida , Mana Tateishi , Keisuke Maeda , Katsuya Iijima , Hiroyuki Shimada , Tatsuro Inoue , Minoru Yamada , Ryo Momosaki , Hidetaka Wakabayashi , Koichi Yamamoto , Hidenori Arai

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引用次数: 0

Abstract

Background

While the digital-based interventions targeting older adults to prevent age-related health problems such as sarcopenia have grown rapidly in recent years, there are no meta-analyses indicating synthesized pooled estimates.

Objective

To examine the effects of digital-based interventions on sarcopenia-related measures, including physical performance and muscle mass, in healthy community-dwelling older adults.

Methods

Systematic searches were performed on MEDLINE, Web of Science, and Cochrane Library for eligible studies published up to 31 March 2023. The mean difference with a 95 % confidence interval was calculated. Methodological quality was assessed using Cochrane RoB 2.0. The GRADE criteria were used to assess evidence certainty.

Results

Thirteen randomized controlled trials with 742 participants were included in the meta-analysis. Handgrip strength, usual walking speed, five times sit-to-stand performance, and 30-second chair stand test showed significant enhancements with the digital-based interventions. However, there were no significant effects of digital-based interventions in appendicular muscle mass. The overall evidence certainty was low.

Conclusions

Although digital-based interventions for healthy older adults are effective in improving physical functions, evidence certainty is low. Additional randomized controlled trials are thus required to further validate the findings.

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基于数字的干预措施对健康老年人肌肉减少症合格标准结果的影响：系统回顾和荟萃分析

背景：近年来，针对老年人预防与年龄相关的健康问题（如肌肉减少症）的数字化干预措施增长迅速，但没有荟萃分析表明综合估计。目的：研究基于数字的干预措施对健康社区老年人肌肉减少症相关措施的影响，包括身体表现和肌肉质量。方法：系统检索MEDLINE、Web of Science和Cochrane Library，检索截至2023年3月31日发表的符合条件的研究。计算平均差值，置信区间为95% %。采用Cochrane RoB 2.0评价方法学质量。GRADE标准用于评估证据的确定性。结果：meta分析纳入13项随机对照试验，共742名受试者。手部握力、通常的行走速度、5次坐立表现和30秒的椅子站立测试显示，数字干预显著增强。然而，基于数字的干预对阑尾肌肉质量没有显著影响。总体证据确定性较低。结论：尽管基于数字的健康老年人干预措施在改善身体功能方面是有效的，但证据确定性很低。因此，需要额外的随机对照试验来进一步验证这些发现。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Ageing Research Reviews 医学-老年医学

CiteScore

19.80

自引率

2.30%

发文量

216

审稿时长

55 days

期刊介绍： With the rise in average human life expectancy, the impact of ageing and age-related diseases on our society has become increasingly significant. Ageing research is now a focal point for numerous laboratories, encompassing leaders in genetics, molecular and cellular biology, biochemistry, and behavior. Ageing Research Reviews (ARR) serves as a cornerstone in this field, addressing emerging trends. ARR aims to fill a substantial gap by providing critical reviews and viewpoints on evolving discoveries concerning the mechanisms of ageing and age-related diseases. The rapid progress in understanding the mechanisms controlling cellular proliferation, differentiation, and survival is unveiling new insights into the regulation of ageing. From telomerase to stem cells, and from energy to oxyradical metabolism, we are witnessing an exciting era in the multidisciplinary field of ageing research. The journal explores the cellular and molecular foundations of interventions that extend lifespan, such as caloric restriction. It identifies the underpinnings of manipulations that extend lifespan, shedding light on novel approaches for preventing age-related diseases. ARR publishes articles on focused topics selected from the expansive field of ageing research, with a particular emphasis on the cellular and molecular mechanisms of the aging process. This includes age-related diseases like cancer, cardiovascular disease, diabetes, and neurodegenerative disorders. The journal also covers applications of basic ageing research to lifespan extension and disease prevention, offering a comprehensive platform for advancing our understanding of this critical field.