Hannah L Hanania, Rohit Gupta, Amanda Marsiglia, Raegan Hunt
{"title":"Poorer Treatment Response in Confluent and Reticulated Papillomatosis Patients With Obesity: A Retrospective Study.","authors":"Hannah L Hanania, Rohit Gupta, Amanda Marsiglia, Raegan Hunt","doi":"10.1111/pde.15871","DOIUrl":null,"url":null,"abstract":"<p><p>An association between confluent and reticulated papillomatosis (CARP) and obesity has been reported; however, the relationship between CARP treatment response and obesity remains unknown. A retrospective chart review was performed of 92 pediatric patients diagnosed and treated for CARP during a 7-year period at a single institution. Twenty-three non-obese patients responded to therapy at a higher rate compared to 69 obese patients (100% vs. 77.5%; p = 0.009) regardless of treatment duration, treatment type, age, or sex, based on multivariable analysis. Our results demonstrate an association between obesity and poorer treatment response necessitating prospective research to better investigate the relationship between CARP severity, weight class, and optimization of medical therapy.</p>","PeriodicalId":19819,"journal":{"name":"Pediatric Dermatology","volume":" ","pages":""},"PeriodicalIF":1.2000,"publicationDate":"2025-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pediatric Dermatology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1111/pde.15871","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"DERMATOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
An association between confluent and reticulated papillomatosis (CARP) and obesity has been reported; however, the relationship between CARP treatment response and obesity remains unknown. A retrospective chart review was performed of 92 pediatric patients diagnosed and treated for CARP during a 7-year period at a single institution. Twenty-three non-obese patients responded to therapy at a higher rate compared to 69 obese patients (100% vs. 77.5%; p = 0.009) regardless of treatment duration, treatment type, age, or sex, based on multivariable analysis. Our results demonstrate an association between obesity and poorer treatment response necessitating prospective research to better investigate the relationship between CARP severity, weight class, and optimization of medical therapy.
期刊介绍：
Pediatric Dermatology answers the need for new ideas and strategies for today''s pediatrician or dermatologist. As a teaching vehicle, the Journal is still unsurpassed and it will continue to present the latest on topics such as hemangiomas, atopic dermatitis, rare and unusual presentations of childhood diseases, neonatal medicine, and therapeutic advances. As important progress is made in any area involving infants and children, Pediatric Dermatology is there to publish the findings.
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