Effect of comorbid allergic diseases on attention-deficit hyperactivity disorder symptoms and sleep: A cross-sectional study

IF 2.9 2区医学 Q1 EDUCATION, SPECIAL

Research in Developmental Disabilities Pub Date : 2025-02-01 DOI:10.1016/j.ridd.2024.104907

Zhang Panpan , Liu Yang , Ma Tao , Tian Chong , Cao Fan , Sun Hao , Xiao Xuwu

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引用次数: 0

Abstract

Introduction

Recent studies have shown a close relationship between attention-deficit hyperactivity disorder (ADHD) and allergic diseases in children. Regrettably, few studies have investigated the effect of comorbid allergies on ADHD symptoms and sleep, in particular, it is unclear whether comorbid allergic conditions further exacerbate sleep problems in children with ADHD.

Objective

To investigate the effect of comorbid allergic on symptoms and sleep in children with ADHD.

Methods

This was a cross-sectional study, 222 ADHD children (aged 6–14 years) were enrolled in, of whom 93 had allergic diseases and 129 without allergic diseases. Collected all ADHD symptom severity and functional impairment scales, including: Swanson, Nolan and Pelham (SNAP) scale, Integrated Visual and Auditory Continuous Performance Test (IVA-CPT), Conners Parents Symptom questionnaire (PSQ) and Weiss Functional Impairment Rating Scale-Parent Form (WFIRS-P). Every guardian of children diagnosed with ADHD is required to complete the Children’s Sleep Habits Questionnaire (CSHQ).

Results

Compared to ADHD children without allergic diseases, we observed significantly higher hyperactivity and impulsivity scores on the SNAP-IV, higher hyperactivity index and impulsivity index on the PSQ, and higher risky activities on the WFIRS-P in ADHD children with comorbid allergic diseases (all p < 0.05). CSHQ total score and sleep disordered breathing were particularly prominent in ADHD children with comorbid allergic diseases (all p < 0.05), and changes in CSHQ correlate with ADHD symptoms and functional impairment. Further analyses revealed that ADHD symptoms and sleep did not worsen with increasing number of comorbid allergic diseases (all p > 0.05). The primary influence on ADHD symptoms and sleep was the type of allergic diseases, where food allergies predominantly influence ADHD symptoms, including attention deficit disorder and hyperactivity disorder (all p < 0.05); allergic rhinitis notably impacts parasomnias, sleep disordered breathing (all p < 0.05); and allergic asthma significantly affects sleep anxiety, daytime sleepiness, and sleep disordered breathing in children with ADHD (all p < 0.05).

Conclusion

The presence of comorbid allergic diseases affects both the hyperactivity and impulsivity symptoms of ADHD and sleep disordered breathing, predominantly influenced by the type of the allergic diseases.

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合并症过敏性疾病对注意缺陷多动障碍症状和睡眠的影响：一项横断面研究。

近年来的研究表明，儿童注意力缺陷多动障碍（ADHD）与过敏性疾病密切相关。遗憾的是，很少有研究调查共病过敏对ADHD症状和睡眠的影响，特别是，尚不清楚共病过敏是否会进一步加剧ADHD儿童的睡眠问题。目的：探讨共病性过敏对ADHD患儿症状及睡眠的影响。方法：采用横断面研究方法，纳入222例6-14岁ADHD儿童，其中93例有过敏性疾病，129例无过敏性疾病。收集所有ADHD症状严重程度和功能障碍量表，包括：Swanson， Nolan and Pelham （SNAP）量表、综合视觉和听觉持续表现测试（IVA-CPT）、Conners家长症状问卷（PSQ）和Weiss功能障碍评定量表-家长表格（WFIRS-P）。每个被诊断患有多动症的儿童的监护人都需要完成儿童睡眠习惯问卷（CSHQ）。结果：与无变应性疾病的ADHD儿童相比，伴发变应性疾病的ADHD儿童SNAP-IV多动和冲动得分显著增高，PSQ多动指数和冲动指数显著增高，WFIRS-P危险活动显著增高（均p  0.05）。对ADHD症状和睡眠的主要影响因素是过敏性疾病的类型，其中食物过敏主要影响ADHD症状，包括注意缺陷障碍和多动障碍（均p ）结论：共病性过敏性疾病的存在既影响ADHD的多动和冲动症状，也影响睡眠呼吸障碍，主要受过敏性疾病类型的影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Research in Developmental Disabilities Multiple-

CiteScore

5.50

自引率

6.50%

发文量

178

期刊介绍： Research In Developmental Disabilities is aimed at publishing original research of an interdisciplinary nature that has a direct bearing on the remediation of problems associated with developmental disabilities. Manuscripts will be solicited throughout the world. Articles will be primarily empirical studies, although an occasional position paper or review will be accepted. The aim of the journal will be to publish articles on all aspects of research with the developmentally disabled, with any methodologically sound approach being acceptable.