Comparison of functional, structural and vascular characteristics between dominant and nondominant eyes.

IF 2.6 4区医学 Q2 OPHTHALMOLOGY

Documenta Ophthalmologica Pub Date : 2024-12-29 DOI:10.1007/s10633-024-10001-2

Mualla Hamurcu, Burcu Polat Gültekin, Melisa Tuncer Göçmen, Zarife Nurbanu Mendi

{"title":"Comparison of functional, structural and vascular characteristics between dominant and nondominant eyes.","authors":"Mualla Hamurcu, Burcu Polat Gültekin, Melisa Tuncer Göçmen, Zarife Nurbanu Mendi","doi":"10.1007/s10633-024-10001-2","DOIUrl":null,"url":null,"abstract":"Purpose: The aim of this study was to compare retinal and optic disc functions as well as vascular structures in dominant eyes (DE) and non-dominant eyes (NDE) among healthy adults using pattern electroretinogram (PERG), optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) tests.Methods: Seventy-two eyes of 36 healthy subjects with bilateral visual acuity of 1.0 were included. Parameters such as intraocular pressure (IOP), cycloplegic spherical equivalent value (SE), PERG, retinal nerve fiber layer (RNFL) thicknesses and OCTA measurements were evaluated. Ocular dominance was determined using the hole-in-the-card test.Results: Of the participants, 67% were female, with a median age of 28 (min-max.18-35) years. Right eye dominance was observed in 61.2% of cases, while left eye dominance was seen in 38.8%. There was no significant difference in refractive values between eyes with right and left eye dominance (0.60 ± 0.40 and 0.41 ± 0.28, p = 0.42). The dominant eyes showed significantly higher P50 amplitude (10.2 µV vs. 9.2 µV, p = 0.003) and shorter peak time (47.9 ms. vs. 48.6 ms, p = 0.01) when compared to the nondominant eyes. There were comparable values in the peak times and amplitudes of the N95 component between the dominant and nondominant eyes. The RNFL layer was thicker on average (p, 0.001) as well as in the nasal and inferior quadrants of the dominant eyes (p < 0.05). OCTA analysis revealed no significant differences in the peripapillary and macular capillary vascular densities between dominant and nondominant eyes (p > 0.05), except for the deep whole capillary density in the macula, which was significantly higher in the dominant eyes (p = 0.02).Conclusion: Our results indicate the existence of functional and structural relationships related to ocular dominance. Future studies provide further insights into ocular dominance and its relationship with eye structure.","PeriodicalId":11207,"journal":{"name":"Documenta Ophthalmologica","volume":" ","pages":""},"PeriodicalIF":2.6000,"publicationDate":"2024-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Documenta Ophthalmologica","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s10633-024-10001-2","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Purpose: The aim of this study was to compare retinal and optic disc functions as well as vascular structures in dominant eyes (DE) and non-dominant eyes (NDE) among healthy adults using pattern electroretinogram (PERG), optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) tests.

Methods: Seventy-two eyes of 36 healthy subjects with bilateral visual acuity of 1.0 were included. Parameters such as intraocular pressure (IOP), cycloplegic spherical equivalent value (SE), PERG, retinal nerve fiber layer (RNFL) thicknesses and OCTA measurements were evaluated. Ocular dominance was determined using the hole-in-the-card test.

Results: Of the participants, 67% were female, with a median age of 28 (min-max.18-35) years. Right eye dominance was observed in 61.2% of cases, while left eye dominance was seen in 38.8%. There was no significant difference in refractive values between eyes with right and left eye dominance (0.60 ± 0.40 and 0.41 ± 0.28, p = 0.42). The dominant eyes showed significantly higher P50 amplitude (10.2 µV vs. 9.2 µV, p = 0.003) and shorter peak time (47.9 ms. vs. 48.6 ms, p = 0.01) when compared to the nondominant eyes. There were comparable values in the peak times and amplitudes of the N95 component between the dominant and nondominant eyes. The RNFL layer was thicker on average (p, 0.001) as well as in the nasal and inferior quadrants of the dominant eyes (p < 0.05). OCTA analysis revealed no significant differences in the peripapillary and macular capillary vascular densities between dominant and nondominant eyes (p > 0.05), except for the deep whole capillary density in the macula, which was significantly higher in the dominant eyes (p = 0.02).

Conclusion: Our results indicate the existence of functional and structural relationships related to ocular dominance. Future studies provide further insights into ocular dominance and its relationship with eye structure.

查看原文本刊更多论文

求助全文

约1分钟内获得全文求助全文

来源期刊

Documenta Ophthalmologica 医学-眼科学

CiteScore

3.50

自引率

21.40%

发文量

审稿时长

>12 weeks

期刊介绍： Documenta Ophthalmologica is an official publication of the International Society for Clinical Electrophysiology of Vision. The purpose of the journal is to promote the understanding and application of clinical electrophysiology of vision. Documenta Ophthalmologica will publish reviews, research articles, technical notes, brief reports and case studies which inform the readers about basic and clinical sciences related to visual electrodiagnosis and means to improve diagnosis and clinical management of patients using visual electrophysiology. Studies may involve animals or humans. In either case appropriate care must be taken to follow the Declaration of Helsinki for human subject or appropriate humane standards of animal care (e.g., the ARVO standards on Animal Care and Use).