Occurrence of ochratoxins in coffee and risk assessment of ochratoxin a in a Costa Rican urban population.

IF 2.3 3区 农林科学 Q2 CHEMISTRY, APPLIED
Daniela Jaikel-Viquez, Fabio Granados, Alejandra Gómez-Arrieta, Josué Vásquez-Flores, Fernando Morales-Calvo, Nicole Argeñal-Avendaño, Delia Álvarez-Corvo, Graciela Artavia, Georgina Gómez-Salas, Bing Wang, Mauricio Redondo-Solano
{"title":"Occurrence of ochratoxins in coffee and risk assessment of ochratoxin a in a Costa Rican urban population.","authors":"Daniela Jaikel-Viquez, Fabio Granados, Alejandra Gómez-Arrieta, Josué Vásquez-Flores, Fernando Morales-Calvo, Nicole Argeñal-Avendaño, Delia Álvarez-Corvo, Graciela Artavia, Georgina Gómez-Salas, Bing Wang, Mauricio Redondo-Solano","doi":"10.1080/19440049.2024.2429140","DOIUrl":null,"url":null,"abstract":"<p><p>Costa Rica is a coffee producer and consumer country, but this product is prone to ochratoxin contamination; therefore, this study aims evaluates the human health risk associated with ochratoxin exposure among coffee consumers in the Costa Rica. Ochratoxin A (OTA) is a nephrotoxic compound classified as a Group 2B carcinogen, produced by the fungi <i>Aspergillus</i> section <i>Circumdati</i>, <i>Aspergillus</i> section <i>Nigri</i> and <i>Penicillium</i> spp.  The presence of OTA and ochratoxin B (OTB) in Costa Rican coffee products (<i>n</i> = 175) was determined by HPLC with fluorescence detection. OTA was detected in 58.2% of the green coffee beans (1.01 ± 0.85 ng g <sup>-1</sup>), in 36.8% of the pure roasted coffee (2.59 ± 4.41 ng g <sup>-1</sup>), in 23.1% of the sugar-added roasted coffee (1.59 ± 0.33 ng g<sup>-1</sup>) and 75% of the instant coffee samples (0.69 ± 0.58 ng g<sup>-1</sup>). The contamination with OTB was 45.5% (1.28 ± 0.83 ng g <sup>-1</sup>), 31.6% (1.60 ± 2.04 ng g <sup>-1</sup>), 30.8% (1.42 ± 0.86 ng g <sup>-1</sup>), and 41.7% (2.64 ± 2.07 ng g <sup>-1</sup>), respectively. The dietary exposure to OTA of the Costa Rican population was assessed by a probabilistic approach. The mean estimated daily intake (EDI) of OTA from coffee was: 0.184 (90% IC: 0.179-0.189) ng kg<sup>-1</sup> bw day<sup>-1</sup> for the total population (0.189 [90% IC: 0.184-0.194] ng kg<sup>-1</sup> bw day<sup>-1</sup> for males and 0.181 [90% IC: 0.176-0.186] ng kg<sup>-1</sup> bw day<sup>-1</sup> for females).  The EDIs were lower than the tolerable human intake benchmarks for OTA set by international food safety authorities (even though more than 80% of OTA is extracted during coffee preparation). The results evidence a low risk (related to ochratoxin) for coffee consumers in Costa Rica.</p>","PeriodicalId":12295,"journal":{"name":"Food Additives and Contaminants Part A-chemistry Analysis Control Exposure & Risk Assessment","volume":" ","pages":"103-116"},"PeriodicalIF":2.3000,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Food Additives and Contaminants Part A-chemistry Analysis Control Exposure & Risk Assessment","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.1080/19440049.2024.2429140","RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/12/2 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"CHEMISTRY, APPLIED","Score":null,"Total":0}
引用次数: 0

Abstract

Costa Rica is a coffee producer and consumer country, but this product is prone to ochratoxin contamination; therefore, this study aims evaluates the human health risk associated with ochratoxin exposure among coffee consumers in the Costa Rica. Ochratoxin A (OTA) is a nephrotoxic compound classified as a Group 2B carcinogen, produced by the fungi Aspergillus section Circumdati, Aspergillus section Nigri and Penicillium spp.  The presence of OTA and ochratoxin B (OTB) in Costa Rican coffee products (n = 175) was determined by HPLC with fluorescence detection. OTA was detected in 58.2% of the green coffee beans (1.01 ± 0.85 ng g -1), in 36.8% of the pure roasted coffee (2.59 ± 4.41 ng g -1), in 23.1% of the sugar-added roasted coffee (1.59 ± 0.33 ng g-1) and 75% of the instant coffee samples (0.69 ± 0.58 ng g-1). The contamination with OTB was 45.5% (1.28 ± 0.83 ng g -1), 31.6% (1.60 ± 2.04 ng g -1), 30.8% (1.42 ± 0.86 ng g -1), and 41.7% (2.64 ± 2.07 ng g -1), respectively. The dietary exposure to OTA of the Costa Rican population was assessed by a probabilistic approach. The mean estimated daily intake (EDI) of OTA from coffee was: 0.184 (90% IC: 0.179-0.189) ng kg-1 bw day-1 for the total population (0.189 [90% IC: 0.184-0.194] ng kg-1 bw day-1 for males and 0.181 [90% IC: 0.176-0.186] ng kg-1 bw day-1 for females).  The EDIs were lower than the tolerable human intake benchmarks for OTA set by international food safety authorities (even though more than 80% of OTA is extracted during coffee preparation). The results evidence a low risk (related to ochratoxin) for coffee consumers in Costa Rica.

咖啡中赭曲霉毒素的发生及哥斯达黎加城市人群赭曲霉毒素a的风险评估。
哥斯达黎加是咖啡生产国和消费国,但这种产品容易受到赭曲霉毒素污染;因此,本研究旨在评估哥斯达黎加咖啡消费者中与赭曲霉毒素接触相关的人类健康风险。赭曲霉毒素A (Ochratoxin A, OTA)是一种被归类为2B类致癌物的肾毒性化合物,由环曲霉、黑曲霉和青霉等真菌产生。  采用HPLC荧光检测法测定了哥斯达黎加咖啡产品(n = 175)中OTA和赭曲霉毒素B (Ochratoxin B, OTB)的含量。在58.2%的生咖啡豆(1.01±0.85 ng g-1), 36.8%的纯烘焙咖啡(2.59±4.41 ng g-1), 23.1%的加糖烘焙咖啡(1.59±0.33 ng g-1)和75%的速溶咖啡样品(0.69±0.58 ng g-1)中检测到OTA。obb污染率分别为45.5%(1.28±0.83 ng g -1)、31.6%(1.60±2.04 ng g -1)、30.8%(1.42±0.86 ng g -1)和41.7%(2.64±2.07 ng g -1)。通过概率方法评估哥斯达黎加人群的饮食暴露于OTA。总体人群从咖啡中获得的OTA平均每日摄入量(EDI)为:0.184 (90% IC: 0.179-0.189) ng kg-1 bw day-1(男性0.189 [90% IC: 0.184-0.194] ng kg-1 bw day-1,女性0.181 [90% IC: 0.176-0.186] ng kg-1 bw day-1)。 EDIs低于国际食品安全当局设定的可容忍的OTA人体摄入量基准(尽管超过80%的OTA是在咖啡制备过程中提取的)。结果表明哥斯达黎加咖啡消费者的风险(与赭曲霉毒素有关)较低。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
7.40
自引率
6.90%
发文量
136
审稿时长
3 months
期刊介绍: Food Additives & Contaminants: Part A publishes original research papers and critical reviews covering analytical methodology, occurrence, persistence, safety evaluation, detoxification and regulatory control of natural and man-made additives and contaminants in the food and animal feed chain. Papers are published in the areas of food additives including flavourings, pesticide and veterinary drug residues, environmental contaminants, plant toxins, mycotoxins, marine biotoxins, trace elements, migration from food packaging, food process contaminants, adulteration, authenticity and allergenicity of foods. Papers are published on animal feed where residues and contaminants can give rise to food safety concerns. Contributions cover chemistry, biochemistry and bioavailability of these substances, factors affecting levels during production, processing, packaging and storage; the development of novel foods and processes; exposure and risk assessment.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信