Neck circumference, waist-to-height ratio, Chinese visceral adiposity index and incident heart failure.

IF 4.4 2区医学 Q1 NUTRITION & DIETETICS

Nutrition Journal Pub Date : 2024-11-28 DOI:10.1186/s12937-024-01048-7

Zhijun Wu, Zhe Huang, Liang Sun, Yuang Fu, Shuohua Chen, Shouling Wu, Xiang Gao

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引用次数: 0

Abstract

Background: The indicators of abdominal obesity have shown to be associated with a high risk of cardiovascular diseases (CVDs), even adjusted for body mass index (BMI). We aimed to investigate the association between neck circumference, waist-to-height ratio (WHtR), Chinese visceral adiposity index (CVAI) and incident heart failure (HF) in Chinese adults.

Methods: The current study included 86,546 participants from two independent cohorts: the Kailuan I study established in 2006 and the Kailuan study II established in 2008. Participants aged 18-80 years who were free of CVDs or cancer were recruited at baseline. The values of neck circumference, WHtR and CVAI were available in 2014. The trajectory analysis was conducted using repeated measures of WHtR and CVAI in the 2008, 2010, 2012 and 2014 surveys. The incident HF cases were identified via reviewing medical records by cardiologists.

Results: During a mean follow-up of 5.62 years, 724 incident HF cases were documented. The highest quartiles of neck circumference, WHtR and CVAI respectively, were significantly associated with a high risk of HF compared to the lowest quartiles of adiposity measures (neck circumference: HR:1.30, 95%CI: 1.03-1.65; WHtR: HR:1.49, 95%CI: 1.16-1.92; and CVAI: HR:1.98, 95%CI: 1.48-2.65). The combination of adiposity measures with BMI or metabolic abnormalities jointly predicted incident HF. Presence of hypertension and diabetes appeared to be the major mediators, accounting for ∼ 8.11-24.7% of the associations between three indicators of abdominal obesity and HF risk.

Conclusion: The new indices of abdominal adiposity could help to identify those who were at a high risk of HF, especially in the presence of high BMI or metabolic abnormalities.

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颈围、腰高比、中国内脏脂肪指数与心力衰竭发生率。

背景：腹部肥胖的指标已被证明与心血管疾病（cvd）的高风险相关，甚至根据体重指数（BMI）进行了调整。我们旨在研究中国成年人颈围、腰高比（WHtR）、中国内脏脂肪指数（CVAI）与心力衰竭（HF）的关系。方法：目前的研究包括来自两个独立队列的86546名参与者：2006年建立的开滦1号研究和2008年建立的开滦2号研究。年龄在18-80岁、无心血管疾病或癌症的参与者在基线时被招募。颈围、WHtR、CVAI均为2014年数据。在2008年、2010年、2012年和2014年的调查中，通过重复测量WHtR和CVAI进行轨迹分析。心脏科医生通过查阅病历确定了心衰事件病例。结果：在平均5.62年的随访期间，记录了724例心衰事件。与肥胖指标最低的四分位数相比，颈围最高的四分位数（WHtR和CVAI）与HF的高风险显著相关(颈围：HR:1.30, 95%CI: 1.03-1.65；WHtR: HR:1.49, 95%CI: 1.16-1.92；CVAI: HR:1.98, 95%CI: 1.48 ~ 2.65)。肥胖测量与BMI或代谢异常联合预测HF的发生。高血压和糖尿病的存在似乎是主要的中介因素，占腹部肥胖和HF风险三个指标之间关联的8.11-24.7%。结论：腹部肥胖的新指标有助于识别HF的高危人群，特别是存在高BMI或代谢异常的人群。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nutrition Journal NUTRITION & DIETETICS-

CiteScore

9.80

自引率

0.00%

发文量

审稿时长

4-8 weeks

期刊介绍： Nutrition Journal publishes surveillance, epidemiologic, and intervention research that sheds light on i) influences (e.g., familial, environmental) on eating patterns; ii) associations between eating patterns and health, and iii) strategies to improve eating patterns among populations. The journal also welcomes manuscripts reporting on the psychometric properties (e.g., validity, reliability) and feasibility of methods (e.g., for assessing dietary intake) for human nutrition research. In addition, study protocols for controlled trials and cohort studies, with an emphasis on methods for assessing dietary exposures and outcomes as well as intervention components, will be considered. Manuscripts that consider eating patterns holistically, as opposed to solely reductionist approaches that focus on specific dietary components in isolation, are encouraged. Also encouraged are papers that take a holistic or systems perspective in attempting to understand possible compensatory and differential effects of nutrition interventions. The journal does not consider animal studies. In addition to the influence of eating patterns for human health, we also invite research providing insights into the environmental sustainability of dietary practices. Again, a holistic perspective is encouraged, for example, through the consideration of how eating patterns might maximize both human and planetary health.