Anatomical, functional, and prognostic results of vitrectomy in epiretinal membranes secondary to retinal vein occlusions.

IF 2.1 4区医学 Q2 OPHTHALMOLOGY

Ophthalmologica Pub Date : 2024-11-25 DOI:10.1159/000542770

Yoo-Ri Chung, Adam Mainguy, Irini Chatziralli, Anissa Smaoui, Bahram Bodaghi, Michel Paques, Ramin Tadayoni, Maria Vittoria Cicinelli, Sarah Touhami

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引用次数: 0

Abstract

Introduction: We investigated the anatomical and functional results of vitrectomy associated with the peeling of secondary epiretinal membranes (ERM) in patients with retinal vein occlusion (RVO) and determined the prognostic factors of surgical outcomes.

Methods: This retrospective, multicenter, observational study included 50 patients with RVO who underwent vitrectomy with ERM removal between July 2012 and February 2021. Visual acuity (VA) and central macular thickness (CMT) were investigated up to three years. Univariate analysis identified the predictive factors associated with functional and anatomical outcomes.

Results: Fifty eyes from 50 patients (62% with central RVO) were included. The mean VA of 0.9 ± 0.7 logMAR preoperatively improved to 0.5 ± 0.5 logMAR after 24 months (p=0.01). Anatomically, the mean preoperative CMT was 501 ± 168 μm, decreasing to 348 ± 108 μm at month 24 (p=0.008). By 36 months, VA had improved or stabilized in 90% of the eyes, whereas CMT had reduced by at least 20% from baseline in 80% of the eyes. A lower number of intravitreal injections (IVI) was required after vitrectomy. Worse preoperative VA, absence of preoperative pan-retinal photocoagulation, and postoperative use of adjunctive IVI were associated with VA recovery. Higher baseline CMT and the use of preoperative dexamethasone injections were associated with an improvement in CMT.

Conclusion: Vitrectomy for ERM secondary to RVO was effective in improving VA and recovering CMT for up to 3 years and reduced the number of IVIs.

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视网膜静脉闭塞继发视网膜外膜的玻璃体切除术的解剖、功能和预后效果。

简介我们研究了视网膜静脉闭塞（RVO）患者接受玻璃体切除术并剥离继发性视网膜外膜（ERM）的解剖和功能结果，并确定了手术结果的预后因素：这项回顾性、多中心、观察性研究纳入了2012年7月至2021年2月期间接受玻璃体切除术并切除ERM的50名RVO患者。研究人员对视力（VA）和黄斑中心厚度（CMT）进行了长达三年的调查。单变量分析确定了与功能和解剖结果相关的预测因素：共纳入了 50 名患者的 50 只眼睛（62% 患有中心性 RVO）。平均视力从术前的 0.9 ± 0.7 logMAR 提高到 24 个月后的 0.5 ± 0.5 logMAR（P=0.01）。在解剖学上，术前的平均 CMT 为 501 ± 168 μm，24 个月后下降到 348 ± 108 μm（P=0.008）。到 36 个月时，90% 的眼睛视力得到改善或稳定，而 80% 的眼睛 CMT 比基线值至少减少了 20%。玻璃体切除术后所需的玻璃体内注射（IVI）次数减少。术前视力较差、术前未进行全视网膜光凝以及术后使用辅助 IVI 与视力恢复有关。较高的基线CMT和术前注射地塞米松与CMT的改善有关：结论：对继发于 RVO 的 ERM 进行玻璃体切割术可有效改善视力，恢复 CMT 长达 3 年之久，并减少 IVI 的次数。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Ophthalmologica 医学-眼科学

CiteScore

5.10

自引率

3.80%

发文量

审稿时长

3 months

期刊介绍： Published since 1899, ''Ophthalmologica'' has become a frequently cited guide to international work in clinical and experimental ophthalmology. It contains a selection of patient-oriented contributions covering the etiology of eye diseases, diagnostic techniques, and advances in medical and surgical treatment. Straightforward, factual reporting provides both interesting and useful reading. In addition to original papers, ''Ophthalmologica'' features regularly timely reviews in an effort to keep the reader well informed and updated. The large international circulation of this journal reflects its importance.