What is the most important mechanical factor involved in trapeziometacarpal osteoarthritis development? A sensitivity analysis based on biomechanical modelling.

IF 1.7 4区医学 Q3 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS

Computer Methods in Biomechanics and Biomedical Engineering Pub Date : 2024-11-19 DOI:10.1080/10255842.2024.2430446

Thomas Valerio, Jean-Louis Milan, Benjamin Goislard de Monsabert, Laurent Vigouroux

引用次数: 0

Abstract

Few studies consider the variability of the model parameters. This study aimed to perform a sensitivity analysis of a trapeziometacarpal joint model, by performing 675 finite element simulations built from the combination of different morphologies, joint passive stiffness, and grip strategies to estimate the joint pressure. Pressure variability was significantly more affected by morphology than grip strategy and joint passive stiffness. The effect of morphology and grip strategy on joint pressure was significant. A significant correlation between the trapezium dorso-volar curvature and the joint pressure was found. Morphology seems more important than the other parameters to estimate joint contact pressure correctly.

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什么是参与梯形掌骨性关节炎发展的最重要的机械因素？基于生物力学模型的敏感性分析。

很少有研究考虑到模型参数的可变性。本研究旨在对梯形掌关节模型进行敏感性分析，通过对不同形态、关节被动刚度和抓握策略组合建立的 675 个有限元模拟来估算关节压力。压力变化受形态的影响明显大于抓握策略和关节被动僵硬度。形态和抓握策略对关节压力的影响是显著的。研究发现，梯形背伏弧度与关节压力之间存在明显的相关性。要正确估计关节接触压力，形态似乎比其他参数更重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Computer Methods in Biomechanics and Biomedical Engineering 工程技术-工程：生物医学

CiteScore

4.10

自引率

6.20%

发文量

179

审稿时长

4-8 weeks

期刊介绍： The primary aims of Computer Methods in Biomechanics and Biomedical Engineering are to provide a means of communicating the advances being made in the areas of biomechanics and biomedical engineering and to stimulate interest in the continually emerging computer based technologies which are being applied in these multidisciplinary subjects. Computer Methods in Biomechanics and Biomedical Engineering will also provide a focus for the importance of integrating the disciplines of engineering with medical technology and clinical expertise. Such integration will have a major impact on health care in the future.