Associations and mediating factors between adverse childhood experiences and substance use behaviours in early adulthood: A population-based longitudinal study

IF 3.7 2区医学 Q1 PSYCHOLOGY, CLINICAL

Addictive behaviors Pub Date : 2024-11-01 DOI:10.1016/j.addbeh.2024.108194

Deirdre Mongan , Seán R Millar , Margaret M Brennan , Anne Doyle , Brian Galvin , Noel McCarthy

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引用次数: 0

Abstract

Background

Research has demonstrated positive associations between adverse childhood experiences (ACEs) and substance use behaviours in young adults. However, many of these are based on cross-sectional data. The pathway between ACEs and substance misuse among emerging adults is also not fully understood and few studies have investigated potential mediating factors.

Methods

We analysed data from the Child Cohort of the Growing Up in Ireland study, a nationally representative longitudinal sample of children recruited at 9 years of age (n = 4,729). Logistic regression was used to examine individual and cumulative ACE exposure relationships with substance use at age 20 years. Mediation analyses were used to assess whether parental and peer relationships and school engagement mediate ACE history associations with substance use behaviours.

Results

ACE exposure relationships with current cannabis use, other illicit drug use and problematic drug use were observed. In particular, young adults who had experienced 2 ACEs or 3 + ACEs had an approximate two-fold (OR=1.80, 95 % CI: 1.29, 2.51) and approximate three-fold (OR=2.94, 95 % CI: 2.06, 4.19) increased odds of problematic drug use, respectively, when compared to participants who had experienced no ACEs during the study period. Mediation analyses suggested that parent and peer attachment and liking school partially mediate relationships between ACEs and substance use behaviours.

Conclusions

Children who have experienced ACEs are at higher risk of future substance use and problematic drug use. In supporting these children, identified mediators such as interpersonal relationships and school engagement may help guide selection of prevention interventions.

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童年不良经历与成年早期药物使用行为之间的关联和中介因素：一项基于人口的纵向研究。

背景：研究表明，不良童年经历（ACE）与青少年药物使用行为之间存在正相关。然而，其中许多研究都是基于横断面数据。人们对童年逆境经历（ACE）与新成人药物滥用之间的关系还不十分清楚，很少有研究对潜在的中介因素进行调查：我们分析了 "在爱尔兰成长 "研究的儿童队列数据，这是一个具有全国代表性的 9 岁儿童纵向样本（n = 4729）。我们采用逻辑回归法来研究个体和累积的 ACE 暴露与 20 岁时药物使用的关系。中介分析用于评估父母和同伴关系以及学校参与是否能调节 ACE 历史与药物使用行为之间的关系：结果：观察到 ACE 与当前大麻使用、其他非法药物使用和问题药物使用之间的关系。特别是，与在研究期间没有经历过 ACE 的参与者相比，经历过 2 次 ACE 或 3 + ACE 的年轻成年人使用问题药物的几率分别增加了约 2 倍（OR=1.80，95 % CI：1.29，2.51）和约 3 倍（OR=2.94，95 % CI：2.06，4.19）。中介分析表明，父母和同伴的依恋以及对学校的喜爱在一定程度上调节了ACE与药物使用行为之间的关系：结论：经历过 ACE 的儿童未来使用药物和问题药物的风险较高。在为这些儿童提供支持时，人际关系和学校参与等已确定的中介因素可能有助于指导预防干预措施的选择。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Addictive behaviors 医学-药物滥用

CiteScore

8.40

自引率

4.50%

发文量

283

审稿时长

46 days

期刊介绍： Addictive Behaviors is an international peer-reviewed journal publishing high quality human research on addictive behaviors and disorders since 1975. The journal accepts submissions of full-length papers and short communications on substance-related addictions such as the abuse of alcohol, drugs and nicotine, and behavioral addictions involving gambling and technology. We primarily publish behavioral and psychosocial research but our articles span the fields of psychology, sociology, psychiatry, epidemiology, social policy, medicine, pharmacology and neuroscience. While theoretical orientations are diverse, the emphasis of the journal is primarily empirical. That is, sound experimental design combined with valid, reliable assessment and evaluation procedures are a requisite for acceptance. However, innovative and empirically oriented case studies that might encourage new lines of inquiry are accepted as well. Studies that clearly contribute to current knowledge of etiology, prevention, social policy or treatment are given priority. Scholarly commentaries on topical issues, systematic reviews, and mini reviews are encouraged. We especially welcome multimedia papers that incorporate video or audio components to better display methodology or findings. Studies can also be submitted to Addictive Behaviors? companion title, the open access journal Addictive Behaviors Reports, which has a particular interest in ''non-traditional'', innovative and empirically-oriented research such as negative/null data papers, replication studies, case reports on novel treatments, and cross-cultural research.