Humor processing and its relationship with clinical features in patients with first-episode schizophrenia

IF 2.3 Q2 PSYCHIATRY
{"title":"Humor processing and its relationship with clinical features in patients with first-episode schizophrenia","authors":"","doi":"10.1016/j.scog.2024.100337","DOIUrl":null,"url":null,"abstract":"<div><div>Humor, a higher-order social cognitive process unique to humans, is commonly impaired in patients with chronic schizophrenia. However, humor processing and its association with the clinical characteristics in the early stage of the illness remain unknown. In this study, we investigated humor processing and its relationship with clinical features in patients with first-episode schizophrenia (FES). We recruited 45 patients with FES and 44 healthy controls matched for age, sex, and education level. The participants completed the Picture Humor Processing Task (HPT-p) and Video Humor Processing Task (HPT-v), which evaluated humor comprehension and appreciation, and a questionnaire assessing their humor styles. Clinical participants also completed clinical and social functioning measurements. Signal detection theory analysis was used to calculate the d' and β values, which represent the detection of humor signals in the comprehension phase and inner criteria of the humor appreciation phase, respectively. In the HPT-p, patients with FES showed a higher false alarm rate (<em>p</em> = 0.048) than healthy controls, whereas the hitting rate, signal recognition ability (d' value), and intrinsic evaluation criterion (β value) were comparable between the two participants groups. In the HPT-v, patients with FES showed lower within-group coherence in the funniness rating (<em>p</em> = 0.023) than healthy controls. In addition, the false alarm rate in the HPT-p and negative symptoms effectively predicted social functioning in patients with FES (R<sup>2</sup> = 0.681, <em>p</em> &lt; 0.001). Our results indicate that impairment of humor comprehension in patients with schizophrenia is generated in the first episode and contributes to social functioning deficits, which require early recognition and intervention.</div></div>","PeriodicalId":38119,"journal":{"name":"Schizophrenia Research-Cognition","volume":null,"pages":null},"PeriodicalIF":2.3000,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Schizophrenia Research-Cognition","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2215001324000386","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PSYCHIATRY","Score":null,"Total":0}
引用次数: 0

Abstract

Humor, a higher-order social cognitive process unique to humans, is commonly impaired in patients with chronic schizophrenia. However, humor processing and its association with the clinical characteristics in the early stage of the illness remain unknown. In this study, we investigated humor processing and its relationship with clinical features in patients with first-episode schizophrenia (FES). We recruited 45 patients with FES and 44 healthy controls matched for age, sex, and education level. The participants completed the Picture Humor Processing Task (HPT-p) and Video Humor Processing Task (HPT-v), which evaluated humor comprehension and appreciation, and a questionnaire assessing their humor styles. Clinical participants also completed clinical and social functioning measurements. Signal detection theory analysis was used to calculate the d' and β values, which represent the detection of humor signals in the comprehension phase and inner criteria of the humor appreciation phase, respectively. In the HPT-p, patients with FES showed a higher false alarm rate (p = 0.048) than healthy controls, whereas the hitting rate, signal recognition ability (d' value), and intrinsic evaluation criterion (β value) were comparable between the two participants groups. In the HPT-v, patients with FES showed lower within-group coherence in the funniness rating (p = 0.023) than healthy controls. In addition, the false alarm rate in the HPT-p and negative symptoms effectively predicted social functioning in patients with FES (R2 = 0.681, p < 0.001). Our results indicate that impairment of humor comprehension in patients with schizophrenia is generated in the first episode and contributes to social functioning deficits, which require early recognition and intervention.
首发精神分裂症患者的幽默处理及其与临床特征的关系
幽默是人类特有的一种高阶社会认知过程,在慢性精神分裂症患者中普遍存在障碍。然而,幽默加工及其与疾病早期临床特征的关系仍不为人知。在这项研究中,我们调查了首发精神分裂症(FES)患者的幽默加工及其与临床特征的关系。我们招募了 45 名首发精神分裂症患者和 44 名在年龄、性别和教育程度方面匹配的健康对照者。参与者完成了图片幽默处理任务(HPT-p)和视频幽默处理任务(HPT-v)(评估幽默理解和欣赏能力),以及一份评估其幽默风格的问卷。临床参与者还完成了临床和社会功能测量。信号检测理论分析用于计算 d' 和 β 值,它们分别代表了理解阶段的幽默信号检测和幽默欣赏阶段的内在标准。在 HPT-p 中,FES 患者的误报率(p = 0.048)高于健康对照组,而两组参与者的命中率、信号识别能力(d'值)和内在评价标准(β 值)相当。在 HPT-v 中,FES 患者在趣味性评分方面的组内一致性(p = 0.023)低于健康对照组。此外,HPT-p 中的误报率和消极症状能有效预测 FES 患者的社会功能(R2 = 0.681,p < 0.001)。我们的研究结果表明,精神分裂症患者的幽默理解能力在首次发作时就会受损,并导致社交功能缺陷,这需要早期识别和干预。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
5.60
自引率
10.70%
发文量
54
审稿时长
67 days
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信