Pediatric Topical Steroid Withdrawal Syndrome: What Is Known, What Is Unknown.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-11-04 DOI:10.1111/pde.15799

Kripa Ahuja, Peter Lio

引用次数: 0

Abstract

Topical steroid withdrawal syndrome (TSW) is a debated condition marked by burning erythema, severe itching, and dry skin following the discontinuation of topical corticosteroids (TCS). This study reviewed reported pediatric TSW cases. With a total of 21 cases reported (inconsistent data provided), 60% (6/10) used TCS on the face; 69% (9/13) were associated with an escalation in potency of TCS and 75% (3/4) were the erythematoedematous variant. Overall, data on TSW in children is lacking and standardized diagnostic criteria are needed.

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小儿外用类固醇戒断综合征：已知与未知。

外用类固醇停药综合征（TSW）是一种备受争议的病症，停用外用皮质类固醇（TCS）后会出现灼热性红斑、严重瘙痒和皮肤干燥。本研究回顾了已报道的儿科 TSW 病例。共报告了 21 个病例（提供的数据不一致），60%（6/10）的病例在面部使用了 TCS；69%（9/13）的病例与 TCS 药效升级有关，75%（3/4）的病例为红斑性水肿变异型。总的来说，目前还缺乏有关儿童 TSW 的数据，需要制定标准化的诊断标准。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.