DEK::AFF2 Carcinoma of the Sinonasal Tract and Skull Base

Q1 Medicine

Surgical Pathology Clinics Pub Date : 2024-08-17 DOI:10.1016/j.path.2024.07.008

Jonathan P. Rivera MD , Ying-Ju Kuo MD , Jen-Fan Hang MD

引用次数: 0

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鼻窦和颅底 DEK::AFF2 癌：全面回顾。

DEK::AFF2癌是鼻窦道和颅底的一种新发肿瘤，通常表现为外生和内生的乳头状生长、复杂的吻合小梁、单调的细胞形态、棘层溶解性改变和肿瘤浸润性中性粒细胞。一部分患者会出现明显的浸润和高级别特征，类似于非角化性鳞状细胞癌。腺体分化也很少出现。这种肿瘤经常局部复发，偶尔会出现远处转移。准确诊断需要识别这些关键的组织学特征，然后进行分子确诊。最近，AFF2 免疫组化被证明是一种敏感而特异的辅助标记物。本综述总结了目前对 DEK::AFF2 癌症的认识。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Surgical Pathology Clinics Medicine-Surgery

CiteScore

4.40

自引率

0.00%

发文量

期刊介绍： This newest addition to the Clinics Series keeps you current on the information that is essential to every practicing surgical pathologist, from the latest techniques and approaches to detailed discussions on differential diagnosis. It devotes each and every issue exclusively to surgical pathology and its associated problems and is enhanced by abundant full-color images. Each issue focuses on a single topic-and is overseen by Guest Editors who are experts in their field-providing information of practical value on service while also offering material that increases understanding.