The Effect of Transcranial Direct Current Stimulation on M1 with and without Mirror Visual Feedback on Range of Motion and Hand Grip Strength of the Affected Upper Limb in Children with Spastic Hemiplegic Cerebral Palsy.

IF 0.8 Q4 CLINICAL NEUROLOGY

Iranian Journal of Child Neurology Pub Date : 2024-01-01 Epub Date: 2024-09-29 DOI:10.22037/IJCN.V18I4.45110

Pegah Farzamfar, Ali Heirani, Ehsan Amiri, Mustafa Sedighi, Daniel Gomes da Silva Machado

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引用次数: 0

Abstract

Objectives: This study investigated the effects of transcranial direct current stimulation (tDCS) before and during the mirror visual feedback (MVF) on hand grip strength (HGS) and range of motion of the affected hand in children with spastic hemiplegia cerebral palsy (SHCP).

Materials & methods: Twelve children with SHCP participated in this randomized, crossover, and double-blind study. They were randomly exposed to one of four intervention conditions, including 1) a-tDCS-offline, 2) s-tDCS-offline, 3) a-tDCS-online, and 4) s-tDCS-online, with a one-week interval. Participants in the online condition received either anodal or sham tDCS during MVF, while those in the offline condition received tDCS before performing MVF. The tDCS was applied over the M1 area of the affected hemisphere for 20 minutes at 1 mA intensity. The HGS and range of motion of the wrist and elbow (ROM-W and ROM-E) of the affected limb were measured before (pre) and immediately after (post) interventions in each session.

Results: The results showed that the HGS was significantly higher under a-tDCS-offline (p=0.001), s-tDCS-offline (p=0.004), and s-tDCS-online (p=0.005) compared to the a-tDCS-online. Moreover, the ROM-W was significantly higher under a-tDCS-offline (p=0.034), s-tDCS-offline (0.011), and s-tDCS-online (p=0.027) compared to the a-tDCS-online. Eventually, the ROM-E was significantly higher under a-tDCS-offline, s-tDCS-offline, and s-tDCS-online compared to the a-tDCS-online (p ˂0.001; p ˂0.001; p=0.01, respectively).

Conclusion: The results might have practical implications regarding the timing of the application of tDCS in conjunction with MVF in children with SHCP.

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经颅直流电刺激 M1（有镜像视觉反馈和无镜像视觉反馈）对痉挛性偏瘫脑瘫儿童患侧上肢活动范围和手部握力的影响。

研究目的本研究调查了经颅直流电刺激（tDCS）在镜像视觉反馈（MVF）前和镜像视觉反馈期间对痉挛性偏瘫脑瘫（SHCP）患儿手部握力（HGS）和患侧手部活动范围的影响：12名痉挛性偏瘫儿童参加了这项随机、交叉和双盲研究。他们被随机分配到四种干预条件中的一种，包括：1）a-tDCS-离线；2）s-tDCS-离线；3）a-tDCS-在线；4）s-tDCS-在线。在线条件下的参与者在 MVF 期间接受阳极或假 tDCS，而离线条件下的参与者在进行 MVF 之前接受 tDCS。tDCS 以 1 mA 的强度作用于受影响半球的 M1 区域，持续 20 分钟。在每个疗程的干预前（前）和干预后（后）立即测量患肢的 HGS 以及腕关节和肘关节的运动范围（ROM-W 和 ROM-E）：结果显示，与 a-tDCS-online 相比，a-tDCS-offline（p=0.001）、s-tDCS-offline（p=0.004）和 s-tDCS-online （p=0.005）下的 HGS 明显更高。此外，与a-tDCS-online相比，a-tDCS-offline（p=0.034）、s-tDCS-offline（0.011）和s-tDCS-online（p=0.027）下的ROM-W明显更高。最终，与 a-tDCS-online 相比，a-tDCS-offline、s-tDCS-offline 和 s-tDCS-online 的 ROM-E 明显更高（分别为 p ˂0.001; p ˂0.001; p=0.01）：这些结果可能对SHCP患儿在应用tDCS和MVF的同时应用tDCS具有实际意义。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Iranian Journal of Child Neurology CLINICAL NEUROLOGY-

CiteScore

1.40

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0.00%

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