Unravelling Peptic Ulcers: Comprehensive Insights into Etiology, Diagnosis, Screening Techniques, and Treatment.

IF 2.6 4区 医学 Q2 PHARMACOLOGY & PHARMACY
Rashmi Pathak, Phool Chandra, Neetu Sachan
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引用次数: 0

Abstract

The risk of illnesses is increasing in the modern era due to unhealthy and modern lifestyles. Research has shown that the most frequent acid-induced abrasion, which often occurs in the stomach and proximal duodenum, is gastric and Peptic Ulcer Disease (PUD), which is a primary worldwide health concern. The deformity is characterized by denuded mucosa and spreads into the submucosa. Non-steroidal antiinflammatory drugs (NSAIDs) and H. pylori infections are two common offenders. In the past, it has been thought that dietary variables, stress, and an acidic hypersecretory state encourage mucosal disruption in peptic acid disease patients. Peptic ulcers continue to be a significant health issue because of their potential for substantial consequences, including bleeding, blockage, and perforation, even with advancements in detection and treatment. This review discusses current screening methods for peptic ulcers and the challenges in diagnosis and treatment, emphasizing the need for precise diagnosis and more effective therapies.

解读消化性溃疡:病因、诊断、筛查技术和治疗的全面见解。
由于不健康的现代生活方式,现代人患病的风险越来越高。研究表明,最常见的胃酸引起的磨蚀通常发生在胃和十二指肠近端,即胃病和消化性溃疡病(PUD),这是全世界首要的健康问题。这种畸形的特点是粘膜变性并向粘膜下层蔓延。非甾体抗炎药(NSAIDs)和幽门螺杆菌感染是两种常见的致病因素。过去,人们认为饮食变量、压力和酸性高分泌状态会导致消化性胃酸病患者的粘膜破坏。即使在检测和治疗方面取得了进步,消化性溃疡仍然是一个重大的健康问题,因为它可能造成出血、堵塞和穿孔等严重后果。这篇综述讨论了当前消化性溃疡的筛查方法以及诊断和治疗方面的挑战,强调了精确诊断和更有效疗法的必要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
6.30
自引率
0.00%
发文量
302
审稿时长
2 months
期刊介绍: Current Pharmaceutical Design publishes timely in-depth reviews and research articles from leading pharmaceutical researchers in the field, covering all aspects of current research in rational drug design. Each issue is devoted to a single major therapeutic area guest edited by an acknowledged authority in the field. Each thematic issue of Current Pharmaceutical Design covers all subject areas of major importance to modern drug design including: medicinal chemistry, pharmacology, drug targets and disease mechanism.
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