Mindfulness Training Has Long-Term Therapeutic Benefits in Women With Irritable Bowel Syndrome

IF 3.1 2区心理学 Q2 PSYCHIATRY

Mindfulness Pub Date : 2024-09-16 DOI:10.1007/s12671-024-02435-1

Susan A. Gaylord, Olafur S. Palsson, Eric L. Garland, John Douglas Mann, Karen Bluth, William Whitehead, Keturah R. Faurot

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Abstract

Objectives

Mindfulness training (MT) has been shown to have substantial therapeutic effects on irritable bowel syndrome (IBS) symptom severity, health-related quality of life, and psychological symptoms at 3 months following an 8-week group MT intervention. This study reports a secondary analysis to examine the long-term trajectory of change in these IBS symptoms.

Methods

This study analyzed 6- and 12-month follow-up data collected in a randomized controlled pilot study involving 75 adult women meeting Rome II criteria for IBS assigned to 8 weekly 2-hr sessions plus one half-day intensive of either a group mindfulness training (MT) or a validated IBS support group (SG). Outcome measures included the IBS Symptom Severity Scale (IBS-SSS), the IBS-Quality of Life (IBS-QOL) and Visceral Sensitivity Index (VSI) questionnaires, and the Brief Symptom Inventory-18 psychological distress measure. Measures were mailed to all participants who attended at least one treatment session. Analysis included mixed effects models comparing the trajectory of change over time between groups.

Results

At 6-month follow-up, MT patients had significantly lower mean IBS-SSS scores compared to SG patients (− 123.79 vs. − 51.82, respectively, p = 0.004). At 12-month follow-up, effects were attenuated, with IBS-SSS scores of − 88.93 (p = 0.001) for MT and − 33.63 (p = 0.158) for SG participants, with a clinically important between-group difference of 61 points (p = 0.107). VSI scores significantly improved at both 6- and 12-month follow-up compared to baseline, for the MT group only. Anxiety and depression significantly improved at 6 months, in the MT group only.

Conclusions

Beneficial effects of an 8-week MT program tailored for IBS persist for up to 12 months after the training.

Preregistration

ClinicalTrials.gov identifier: NCT00680693.

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正念训练对患有肠易激综合征的女性有长期治疗效果

目的在接受为期 8 周的正念训练（MT）小组干预 3 个月后，正念训练对肠易激综合征（IBS）症状严重程度、与健康相关的生活质量和心理症状具有显著的治疗效果。本研究对一项随机对照试验研究中收集的 6 个月和 12 个月的随访数据进行了二次分析，该研究涉及 75 名符合罗马 II 肠易激综合征标准的成年女性，她们被分配参加了每周 8 次每次 2 小时的正念训练（MT）小组或经验证的肠易激综合征支持小组（SG）的半天强化训练。结果测量包括肠易激综合征症状严重程度量表（IBS-SSS）、肠易激综合征生活质量（IBS-QOL）和内脏敏感指数（VSI）问卷，以及症状简明量表-18 心理压力测量。所有参加过至少一次治疗的参与者都收到了邮寄的问卷。结果6个月随访时，MT患者的IBS-SSS平均得分明显低于SG患者（分别为-123.79 vs. -51.82，p = 0.004）。在 12 个月的随访中，效果有所减弱，MT 患者的 IBS-SSS 评分为 - 88.93（p = 0.001），SG 患者的 IBS-SSS 评分为 - 33.63（p = 0.158），组间差异为 61 分（p = 0.107），具有重要的临床意义。与基线相比，仅 MT 组在 6 个月和 12 个月的随访中 VSI 分数均有明显改善。结论针对肠易激综合征量身定制的 8 周 MT 课程的益处在训练后的 12 个月内持续存在：NCT00680693。

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来源期刊

Mindfulness Multiple-

CiteScore

6.10

自引率

19.40%

发文量

224

期刊介绍： Mindfulness seeks to advance research, clinical practice, and theory on mindfulness. It is interested in manuscripts from diverse viewpoints, including psychology, psychiatry, medicine, neurobiology, psychoneuroendocrinology, cognitive, behavioral, cultural, philosophy, spirituality, and wisdom traditions. Mindfulness encourages research submissions on the reliability and validity of assessment of mindfulness; clinical uses of mindfulness in psychological distress, psychiatric disorders, and medical conditions; alleviation of personal and societal suffering; the nature and foundations of mindfulness; mechanisms of action; and the use of mindfulness across cultures. The Journal also seeks to promote the use of mindfulness by publishing scholarly papers on the training of clinicians, institutional staff, teachers, parents, and industry personnel in mindful provision of services. Examples of topics include: Mindfulness-based psycho-educational interventions for children with learning, emotional, and behavioral disorders Treating depression and clinical symptoms in patients with chronic heart failure Yoga and mindfulness Cognitive-behavioral mindfulness group therapy interventions Mindfulnessness and emotional regulation difficulties in children Loving-kindness meditation to increase social connectedness Training for parents and children with ADHD Recovery from substance abuse Changing parents’ mindfulness Child management skills Treating childhood anxiety and depression