Medium engineering of lipase-catalyzed reaction using CO2

IF 1.9 4区农林科学 Q3 CHEMISTRY, APPLIED

Journal of the American Oil Chemists Society Pub Date : 2024-09-04 DOI:10.1002/aocs.12895

Tomoko Matsuda, Hai Nam Hoang

引用次数: 0

Abstract

One of the most frequently used biocatalysts for organic synthesis is lipase, a triacylglycerol hydrolase, that also catalyzes esterification in non-aqueous solvents. Various non-aqueous solvents such as organic solvents, ionic liquids, and pressurized carbon dioxide (CO₂) have been employed for lipase-catalyzed reactions. Notably, pressurized CO₂ (supercritical CO₂, liquid CO₂, CO₂-expanded liquid) serves as a functional green solvent. This review briefly outlines the properties of pressurized CO₂ relevant to biocatalysis and provides examples of utilizing pressurized CO₂ solvents for efficient synthesis with immobilized lipases.

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利用二氧化碳进行脂肪酶催化反应的介质工程

脂肪酶是最常用于有机合成的生物催化剂之一，它是一种三酰甘油水解酶，也能在非水溶剂中催化酯化反应。脂肪酶催化反应使用了各种非水溶剂，如有机溶剂、离子液体和加压二氧化碳（CO2）。值得注意的是，加压二氧化碳（超临界二氧化碳、液态二氧化碳、二氧化碳膨胀液）是一种功能性绿色溶剂。本综述简要概述了与生物催化相关的加压二氧化碳的特性，并提供了利用加压二氧化碳溶剂与固定化脂肪酶进行高效合成的实例。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of the American Oil Chemists Society 工程技术-食品科技

CiteScore

4.10

自引率

5.00%

发文量

审稿时长

2.4 months

期刊介绍： The Journal of the American Oil Chemists’ Society (JAOCS) is an international peer-reviewed journal that publishes significant original scientific research and technological advances on fats, oils, oilseed proteins, and related materials through original research articles, invited reviews, short communications, and letters to the editor. We seek to publish reports that will significantly advance scientific understanding through hypothesis driven research, innovations, and important new information pertaining to analysis, properties, processing, products, and applications of these food and industrial resources. Breakthroughs in food science and technology, biotechnology (including genomics, biomechanisms, biocatalysis and bioprocessing), and industrial products and applications are particularly appropriate. JAOCS also considers reports on the lipid composition of new, unique, and traditional sources of lipids that definitively address a research hypothesis and advances scientific understanding. However, the genus and species of the source must be verified by appropriate means of classification. In addition, the GPS location of the harvested materials and seed or vegetative samples should be deposited in an accredited germplasm repository. Compositional data suitable for Original Research Articles must embody replicated estimate of tissue constituents, such as oil, protein, carbohydrate, fatty acid, phospholipid, tocopherol, sterol, and carotenoid compositions. Other components unique to the specific plant or animal source may be reported. Furthermore, lipid composition papers should incorporate elements of yeartoyear, environmental, and/ or cultivar variations through use of appropriate statistical analyses.