Striated duct adenoma: The cytological description of a rare entity.

IF 1.2 4区 医学 Q4 CELL BIOLOGY
Cytopathology Pub Date : 2024-09-09 DOI:10.1111/cyt.13441
Montserrat De La Torre Serrano, Lorenzo Alarcón García, Ana María Colino Gallardo, Jesus Vega-Gonzalez, María Reyes Bergillos Giménez, Desiré Hernandez Martinez, Alejandro Garcia Egido, María Cruz Iglesias Moreno, Pablo Pérez-Alonso, José Carlos Plaza Hernandez, M Jesús Fernández-Aceñero
{"title":"Striated duct adenoma: The cytological description of a rare entity.","authors":"Montserrat De La Torre Serrano, Lorenzo Alarcón García, Ana María Colino Gallardo, Jesus Vega-Gonzalez, María Reyes Bergillos Giménez, Desiré Hernandez Martinez, Alejandro Garcia Egido, María Cruz Iglesias Moreno, Pablo Pérez-Alonso, José Carlos Plaza Hernandez, M Jesús Fernández-Aceñero","doi":"10.1111/cyt.13441","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>Striated duct adenoma is a benign salivary gland tumour recently recognized by the World Health Organization. To date, no report has described the cytological features of this entity.</p><p><strong>Materials and methods: </strong>We report the case of a 60-year-old woman with a tumour in the right parotid gland with a diameter greater than 2.4 cm confirmed by imaging tests.</p><p><strong>Results: </strong>Two fine-needle aspiration cytologies (FNAC) were performed with inconclusive results, reporting epithelioid and spindle-shaped cellularity, with little stroma, and nuclei with abundant pseudoinclusions. Myoepithelioma and Schwannoma were proposed as differential diagnoses. An immunocytochemical panel was performed, showing positivity for S-100, SOX10, CK7 and vimentin, and negativity for both myoepithelial (p63 and calponin) and thyroid markers. In the absence of a conclusive diagnosis, the patient accepted surgery. The biopsy results confirmed diagnosis of striated duct adenoma, with immunohistochemical features superimposable to cytology.</p><p><strong>Conclusion: </strong>Little information is available in the literature, both on biopsy and, more strikingly, on cytology of this neoplasm. The aim of this work is to provide cytological characteristics that allow diagnosis of this entity with FNAC and thus avoid unnecessary surgeries.</p>","PeriodicalId":55187,"journal":{"name":"Cytopathology","volume":null,"pages":null},"PeriodicalIF":1.2000,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cytopathology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1111/cyt.13441","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CELL BIOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Introduction: Striated duct adenoma is a benign salivary gland tumour recently recognized by the World Health Organization. To date, no report has described the cytological features of this entity.

Materials and methods: We report the case of a 60-year-old woman with a tumour in the right parotid gland with a diameter greater than 2.4 cm confirmed by imaging tests.

Results: Two fine-needle aspiration cytologies (FNAC) were performed with inconclusive results, reporting epithelioid and spindle-shaped cellularity, with little stroma, and nuclei with abundant pseudoinclusions. Myoepithelioma and Schwannoma were proposed as differential diagnoses. An immunocytochemical panel was performed, showing positivity for S-100, SOX10, CK7 and vimentin, and negativity for both myoepithelial (p63 and calponin) and thyroid markers. In the absence of a conclusive diagnosis, the patient accepted surgery. The biopsy results confirmed diagnosis of striated duct adenoma, with immunohistochemical features superimposable to cytology.

Conclusion: Little information is available in the literature, both on biopsy and, more strikingly, on cytology of this neoplasm. The aim of this work is to provide cytological characteristics that allow diagnosis of this entity with FNAC and thus avoid unnecessary surgeries.

条状导管腺瘤:一种罕见病例的细胞学描述。
简介条状导管腺瘤是世界卫生组织最近确认的一种良性唾液腺肿瘤。迄今为止,还没有报告描述过这种肿瘤的细胞学特征:我们报告了一例 60 岁女性的病例,她的右侧腮腺肿瘤经影像学检查证实直径超过 2.4 厘米:结果:进行了两次细针穿刺细胞学检查(FNAC),结果均不确定,报告为上皮样和纺锤形细胞,间质少,核内有大量假包涵体。建议将肌上皮瘤和许旺瘤作为鉴别诊断。免疫细胞化学检查显示,S-100、SOX10、CK7和波形蛋白呈阳性,肌上皮(p63和钙蛋白)和甲状腺标志物呈阴性。在没有确诊的情况下,患者接受了手术治疗。活检结果确诊为横纹肌导管腺瘤,免疫组化特征与细胞学特征相叠加:结论:关于这种肿瘤的活检和细胞学方面的文献资料很少。这项工作的目的是提供细胞学特征,以便通过 FNAC 诊断这种肿瘤,从而避免不必要的手术。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Cytopathology
Cytopathology 生物-病理学
CiteScore
2.30
自引率
15.40%
发文量
107
审稿时长
6-12 weeks
期刊介绍: The aim of Cytopathology is to publish articles relating to those aspects of cytology which will increase our knowledge and understanding of the aetiology, diagnosis and management of human disease. It contains original articles and critical reviews on all aspects of clinical cytology in its broadest sense, including: gynaecological and non-gynaecological cytology; fine needle aspiration and screening strategy. Cytopathology welcomes papers and articles on: ultrastructural, histochemical and immunocytochemical studies of the cell; quantitative cytology and DNA hybridization as applied to cytological material.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信