{"title":"Unusual case of prurigo pigmentosa on the upper extremities in an adolescent female: A rare presentation.","authors":"Gökçe Işıl Kurmuş, Laden Elkıran, Dilek Menteşoğlu, Ebru Şebnem Ayva, Selda Pelin Kartal","doi":"10.1111/pde.15731","DOIUrl":null,"url":null,"abstract":"<p><p>A 16-year-old girl developed prurigo pigmentosa (PP) following initiation of a ketogenic diet, presenting with pruritic, erythematous, and brownish papules exclusively on her upper extremities. Histopathological examination revealed mild spongiosis with perivascular neutrophilic and mononuclear cell infiltrate, confirming the diagnosis of PP. Treatment with oral doxycycline and discontinuation of the ketogenic diet led to lesion resolution within one month, with subsequent postinflammatory hyperpigmentation. This case highlights the rarity of PP presenting solely on the upper extremities in pediatric patients, expanding our understanding of this dermatological disease.</p>","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":null,"pages":null},"PeriodicalIF":16.4000,"publicationDate":"2024-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1111/pde.15731","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
A 16-year-old girl developed prurigo pigmentosa (PP) following initiation of a ketogenic diet, presenting with pruritic, erythematous, and brownish papules exclusively on her upper extremities. Histopathological examination revealed mild spongiosis with perivascular neutrophilic and mononuclear cell infiltrate, confirming the diagnosis of PP. Treatment with oral doxycycline and discontinuation of the ketogenic diet led to lesion resolution within one month, with subsequent postinflammatory hyperpigmentation. This case highlights the rarity of PP presenting solely on the upper extremities in pediatric patients, expanding our understanding of this dermatological disease.
期刊介绍:
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.