Highly sensitive SPR based PCF sensor for broader analyte detection range including blood compositions detection

IF 3.1 3区物理与天体物理 Q2 Engineering

Optik Pub Date : 2024-08-27 DOI:10.1016/j.ijleo.2024.172010

Rupam Srivastava, Vinit Kumar, Yogendra Kumar Prajapati

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Abstract

In this manuscript, a photonic crystal fiber (PCF) based sensor working on surface plasmon resonance (SPR) concept, which is polished at both the sides and consisting of semi-circular grooves is presented for the detection of a broad range of analytes with refractive index (RI) from 1.17 to 1.40. Also, the analysis is carried out for the diagnosis of different blood compositions such as water, plasma, white blood cells (WBCs), hemoglobin (HB) and red blood cells (RBCs). Plasmonic material gold is coated in the semi-circular grooves, which causes the strong SPR effect due to reduced distance between core and analyte resulting in excellent detection of the analytes. Thus, the optimum wavelength sensitivity and resolution in the case of broad analyte range detection with RI from 1.17 to 1.40 is obtained as 13000 nm/RIU and 7.7×10⁻⁶ RIU respectively. Also, blood composition detection using the proposed sensor results in excellent sensing performance with the maximum wavelength sensitivity for hemoglobin-RBCs as 11,500 nm/RIU with finer resolution of 8.69×10⁻⁶ RIU.

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基于 SPR 的 PCF 传感器灵敏度高，可用于更广泛的分析物检测范围，包括血液成分检测

本手稿介绍了一种基于表面等离子体共振（SPR）概念的光子晶体光纤（PCF）传感器，该传感器两侧抛光，由半圆形凹槽组成，用于检测折射率（RI）在 1.17 至 1.40 之间的多种分析物。此外，还对不同的血液成分进行了分析诊断，如水、血浆、白细胞（WBC）、血红蛋白（HB）和红细胞（RBC）。在半圆形凹槽中涂覆了等离子材料金，由于缩短了核心与分析物之间的距离，从而产生了强烈的 SPR 效应，实现了对分析物的出色检测。因此，在检测 RI 为 1.17 至 1.40 的宽分析物范围时，最佳波长灵敏度和分辨率分别为 13000 nm/RIU 和 7.7×10-6 RIU。此外，使用拟议的传感器检测血液成分也具有出色的传感性能，血红蛋白-红细胞的最大波长灵敏度为 11,500 nm/RIU，分辨率为 8.69×10-6 RIU。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Optik 物理-光学

CiteScore

6.90

自引率

12.90%

发文量

1471

审稿时长

46 days

期刊介绍： Optik publishes articles on all subjects related to light and electron optics and offers a survey on the state of research and technical development within the following fields: Optics: -Optics design, geometrical and beam optics, wave optics- Optical and micro-optical components, diffractive optics, devices and systems- Photoelectric and optoelectronic devices- Optical properties of materials, nonlinear optics, wave propagation and transmission in homogeneous and inhomogeneous materials- Information optics, image formation and processing, holographic techniques, microscopes and spectrometer techniques, and image analysis- Optical testing and measuring techniques- Optical communication and computing- Physiological optics- As well as other related topics.