The effects of setup parameters on the measured kinetic output of cervical disc prostheses

IF 1.7 4区 医学 Q3 ENGINEERING, BIOMEDICAL
Hossein Ansaripour , Stephen J. Ferguson , Markus Flohr
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引用次数: 0

Abstract

Mechanical testing machines are used to evaluate kinematics, kinetics, wear, and efficacy of spinal implants. The simulation of "physiological" spinal loading conditions necessitates the simultaneous use of multiple actuators. The challenge in achieving a desired loading profile lies in achieving close synchronization of these actuators. Errors in load application can be attributed to both the control system and the intrinsic sample response. Moreover, the presence of friction in the setup can have an impact on the measured outcome. The optimization of setup parameters can substantially improve the ability to simulate spinal loading conditions and obtain reliable data on implant performance. In this study, a reproducible kinematic test protocol was developed to evaluate the sensitivity of the kinetic response (i.e., measured loads, moments, and stiffnesses) of a cervical disc prosthesis to several testing parameters. In this context, five ceramic ball and socket sample implants were mounted in a 6 DOF material testing machine and tested with a constant axial compressive force of 100 N in two motion modes: 1) flexion-extension (±7.5°) and 2) lateral bending (±6°). Parameters including rotation rate, slider friction, friction between the samples' articulating surfaces, and moment arm were considered to determine their effects on measured kinetic parameters. The sensitivity analysis indicated that all setup parameters except friction between the samples' articulating surfaces had a substantial effect on the results. The findings were then compared to predictions from a free body diagram to determine the optimal setup parameters. Consequently, the setup with the lowest rotation rate and employing passive sliders yielded results that were consistent with the free body diagram. This study demonstrated the significance of a comprehensive setup evaluation for reliable and reproducible testing of spinal implants, also for comparison between labs.

设置参数对颈椎椎间盘假体动力输出测量值的影响
机械试验机用于评估脊柱植入物的运动学、动力学、磨损和功效。模拟 "生理 "脊柱加载条件需要同时使用多个致动器。实现理想加载曲线的挑战在于实现这些致动器的紧密同步。加载过程中的误差可归因于控制系统和样本的固有反应。此外,设置中存在的摩擦也会对测量结果产生影响。设置参数的优化可以大大提高模拟脊柱加载条件的能力,并获得有关植入物性能的可靠数据。本研究开发了一种可重复的运动学测试方案,以评估颈椎间盘假体的动力学响应(即测量的载荷、力矩和刚度)对几个测试参数的敏感性。在这种情况下,将五个陶瓷球和套筒样本植入体安装在一台 6 DOF 材料试验机中,在两种运动模式下以 100 N 的恒定轴向压缩力进行测试:1)屈伸(±7.5°)和 2)侧弯(±6°)。考虑的参数包括旋转率、滑块摩擦力、样品铰接面之间的摩擦力和力矩臂,以确定它们对测量的动力学参数的影响。灵敏度分析表明,除样品铰接面之间的摩擦力外,所有设置参数都对结果有很大影响。然后将分析结果与自由体图的预测结果进行比较,以确定最佳设置参数。结果发现,采用最低旋转率和被动滑块的设置结果与自由体图一致。这项研究表明,对脊柱植入物进行可靠、可重复的测试,以及对实验室之间的比较进行全面的设置评估具有重要意义。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Medical Engineering & Physics
Medical Engineering & Physics 工程技术-工程:生物医学
CiteScore
4.30
自引率
4.50%
发文量
172
审稿时长
3.0 months
期刊介绍: Medical Engineering & Physics provides a forum for the publication of the latest developments in biomedical engineering, and reflects the essential multidisciplinary nature of the subject. The journal publishes in-depth critical reviews, scientific papers and technical notes. Our focus encompasses the application of the basic principles of physics and engineering to the development of medical devices and technology, with the ultimate aim of producing improvements in the quality of health care.Topics covered include biomechanics, biomaterials, mechanobiology, rehabilitation engineering, biomedical signal processing and medical device development. Medical Engineering & Physics aims to keep both engineers and clinicians abreast of the latest applications of technology to health care.
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