Test-retest reliability and normative data for “Seven-iTT”, a test for the assessment of taste and oral trigeminal function

IF 2.7 4区 医学 Q2 BIOCHEMICAL RESEARCH METHODS
Mariano Mastinu , Andreas Püschner , Saskia Gerlach, Thomas Hummel
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引用次数: 0

Abstract

Background

Assessment of taste and somatosensory perception in clinical practice lacks fast tests that are validated and reliable. Recently, a 12-item identification test for taste and oral trigeminal perception, and its shorter version, the Seven-iTT, was developed. The objectives of this study were to evaluate its test-retest reliability and establish normative data.

New method

Two-hundred participants (120 women, 80 men) with a good sense of taste performed a whole-mouth identification test using 12 filter-paper strips impregnated with low and high concentrations of sweet, sour, salty, bitter, astringency, and spiciness. Fifty of them repeated the task, with a median interval of 122 days from the first visit. Test-retest reliability was determined using Spearman correlation and the Bland–Altman plot method.

Results

There was a significant correlation in identification score between the first and the second session for both versions of the test (r ≥ 0.28; p ≤ 0.048). The Bland–Altman plot reflected a good congruence between the results of the two sessions. Additionally, frequencies of correct identification were consistent between sessions, with women outperforming men (p = 0.005). Hypogeusia was established at Seven-iTT score of 3 of less.

Comparison with existing methods

The identification test combines taste and somatosensory perception, thus creating a more detailed diagnosis tool. Scores were correlated with self-rated taste perception.

Conclusion

The present results confirmed the applicability of Seven-iTT for a reliable, fast evaluation of taste and somatosensory perception in the general population, that can be extended to clinical practice.

用于评估味觉和口腔三叉神经功能的测试 "Seven-iTT "的重测可靠性和常模数据。
背景:临床实践中对味觉和体感知觉的评估缺乏经过验证且可靠的快速测试。最近,我们开发出了一种由 12 个项目组成的味觉和口腔三叉神经知觉识别测试及其简短版本--Seven-iTT。本研究的目的是评估其测试再测可靠性并建立常模数据:新方法:200 名具有良好味觉的参与者(120 名女性,80 名男性)使用 12 张浸渍有低浓度和高浓度甜味、酸味、咸味、苦味、涩味和辣味的滤纸条进行全口辨别测试。其中 50 人重复进行了这项测试,与第一次测试的间隔时间中位数为 122 天。采用斯皮尔曼相关法和布兰德-阿尔特曼图法测定了重复测试的可靠性:两个版本的测试在第一次和第二次测试的识别得分之间存在明显的相关性(r ≥ 0.28; p ≤ 0.048)。布兰-阿尔特曼曲线图反映了两次测试结果的一致性。此外,两次测试的正确识别频率一致,女性的识别率高于男性(p = 0.005)。Seven-iTT得分在3分以下时,即为地贫:与现有方法的比较:鉴定测试结合了味觉和体感知觉,因此是一种更详细的诊断工具。得分与自评味觉感知相关:本研究结果证实,Seven-iTT 可用于对普通人群的味觉和体感进行可靠、快速的评估,并可推广到临床实践中。
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来源期刊
Journal of Neuroscience Methods
Journal of Neuroscience Methods 医学-神经科学
CiteScore
7.10
自引率
3.30%
发文量
226
审稿时长
52 days
期刊介绍: The Journal of Neuroscience Methods publishes papers that describe new methods that are specifically for neuroscience research conducted in invertebrates, vertebrates or in man. Major methodological improvements or important refinements of established neuroscience methods are also considered for publication. The Journal''s Scope includes all aspects of contemporary neuroscience research, including anatomical, behavioural, biochemical, cellular, computational, molecular, invasive and non-invasive imaging, optogenetic, and physiological research investigations.
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