{"title":"The lubricated matter in body","authors":"Hui Yuan, Wenguo Cui","doi":"10.1016/j.pmatsci.2024.101334","DOIUrl":null,"url":null,"abstract":"<div><p>Lubrication is everywhere in the body and essential for the correct operation of biological systems when subjected to contact stress and wear. The body is like a continuously operating life machine. Friction and energy consumption throughout the body would increase dramatically without lubrication, causing physical damage, accelerating senescence and even endangering life. Therefore, it is vital to propose the notion of body lubrication and investigate in depth the irreplaceable role of lubricated matter in life. However, no article has yet summarized “lubricated matter” throughout the body. The need to understand the origin of the lubricated matter in body is driving this review, which could shed insight into degenerative processes and suggest therapeutic options for body disorders, including osteoarthritis, tendon injury, dry eye, etc. Initially, we present an overview of lubricated model and lubricated medium, and gather together the most important data on coefficient of friction about lubricated fluid and lubricated biomacromolecules in body. Subsequently, lubricated matter in body, such as motor system including joint, tendon, bone, muscle, intervertebral disc, shouldercuff, and ligament; digestive system including mouth, teeth, pharynx, esophagus, stomach, intestine, and peritoneum; respiratory system including nose, lung, trachea, and pleura; circulatory system including heart, blood vessel, urethra, and ureter; nervous system including eye and brain; skin system including skin and hair; and reproductive system including vagina, are emphasized. Following recent advances based on lubrication, the developments of lubricated therapy in body at a molecular level are reviewed. In conclusion, the most significant challenges and opportunities of lubricated matter in body are thoroughly discussed.</p></div>","PeriodicalId":411,"journal":{"name":"Progress in Materials Science","volume":"146 ","pages":"Article 101334"},"PeriodicalIF":33.6000,"publicationDate":"2024-07-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Progress in Materials Science","FirstCategoryId":"88","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0079642524001038","RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
Lubrication is everywhere in the body and essential for the correct operation of biological systems when subjected to contact stress and wear. The body is like a continuously operating life machine. Friction and energy consumption throughout the body would increase dramatically without lubrication, causing physical damage, accelerating senescence and even endangering life. Therefore, it is vital to propose the notion of body lubrication and investigate in depth the irreplaceable role of lubricated matter in life. However, no article has yet summarized “lubricated matter” throughout the body. The need to understand the origin of the lubricated matter in body is driving this review, which could shed insight into degenerative processes and suggest therapeutic options for body disorders, including osteoarthritis, tendon injury, dry eye, etc. Initially, we present an overview of lubricated model and lubricated medium, and gather together the most important data on coefficient of friction about lubricated fluid and lubricated biomacromolecules in body. Subsequently, lubricated matter in body, such as motor system including joint, tendon, bone, muscle, intervertebral disc, shouldercuff, and ligament; digestive system including mouth, teeth, pharynx, esophagus, stomach, intestine, and peritoneum; respiratory system including nose, lung, trachea, and pleura; circulatory system including heart, blood vessel, urethra, and ureter; nervous system including eye and brain; skin system including skin and hair; and reproductive system including vagina, are emphasized. Following recent advances based on lubrication, the developments of lubricated therapy in body at a molecular level are reviewed. In conclusion, the most significant challenges and opportunities of lubricated matter in body are thoroughly discussed.
期刊介绍：
Progress in Materials Science is a journal that publishes authoritative and critical reviews of recent advances in the science of materials. The focus of the journal is on the fundamental aspects of materials science, particularly those concerning microstructure and nanostructure and their relationship to properties. Emphasis is also placed on the thermodynamics, kinetics, mechanisms, and modeling of processes within materials, as well as the understanding of material properties in engineering and other applications.
The journal welcomes reviews from authors who are active leaders in the field of materials science and have a strong scientific track record. Materials of interest include metallic, ceramic, polymeric, biological, medical, and composite materials in all forms.
Manuscripts submitted to Progress in Materials Science are generally longer than those found in other research journals. While the focus is on invited reviews, interested authors may submit a proposal for consideration. Non-invited manuscripts are required to be preceded by the submission of a proposal. Authors publishing in Progress in Materials Science have the option to publish their research via subscription or open access. Open access publication requires the author or research funder to meet a publication fee (APC).
Abstracting and indexing services for Progress in Materials Science include Current Contents, Science Citation Index Expanded, Materials Science Citation Index, Chemical Abstracts, Engineering Index, INSPEC, and Scopus.
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