{"title":"Cognitive complaint inversely associated to UHR transition","authors":"Mirvat Hamdan-Dumont , Laurent Lecardeur , Marine Habert , Jérémy Couturas , Mireille Okassa , Aurélie Lacroix , Benjamin Calvet","doi":"10.1016/j.scog.2024.100319","DOIUrl":null,"url":null,"abstract":"<div><p>The aim of this study was to identify the impact of staging on a six-months transition in Ultra-High Risk (UHR) youth.</p><p>Subjects were enrolled at assessment; evolution was monitored for six months. Clinical determinants (unusual thought content, perceptual abnormalities, cognitive complaint, etc.) were collected.</p><p>37 non-psychotic and 39 UHR subjects were included. 13 UHR (35.2 %) experienced psychotic transition, while none of non-psychotic subjects did log-rank <em>p</em> < 0.001. Self-reported cognitive complaint was inversely associated to transition OR 0.13 95 % IC [0.03–0.64]. Unusual Thought Content was associated to psychotic transition 0R 8.57 95 % IC [1.17–63]. Self-reported cognitive complaint could be a protective transition marker in UHR.</p></div>","PeriodicalId":38119,"journal":{"name":"Schizophrenia Research-Cognition","volume":"38 ","pages":"Article 100319"},"PeriodicalIF":2.3000,"publicationDate":"2024-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2215001324000209/pdfft?md5=d373455968fc954a6210eeb509d5fd3e&pid=1-s2.0-S2215001324000209-main.pdf","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Schizophrenia Research-Cognition","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2215001324000209","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PSYCHIATRY","Score":null,"Total":0}
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Abstract
The aim of this study was to identify the impact of staging on a six-months transition in Ultra-High Risk (UHR) youth.
Subjects were enrolled at assessment; evolution was monitored for six months. Clinical determinants (unusual thought content, perceptual abnormalities, cognitive complaint, etc.) were collected.
37 non-psychotic and 39 UHR subjects were included. 13 UHR (35.2 %) experienced psychotic transition, while none of non-psychotic subjects did log-rank p < 0.001. Self-reported cognitive complaint was inversely associated to transition OR 0.13 95 % IC [0.03–0.64]. Unusual Thought Content was associated to psychotic transition 0R 8.57 95 % IC [1.17–63]. Self-reported cognitive complaint could be a protective transition marker in UHR.
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