Use of anticoagulant drugs for hospitalised patients: A multicentre study

IF 0.5 Q4 EDUCATION, SCIENTIFIC DISCIPLINES

Pharmacy Education Pub Date : 2024-05-12 DOI:10.46542/pe.2024.243.286291

Lily Annisa, Nurfina Dian Kartikawati, V. Ningrum

{"title":"Use of anticoagulant drugs for hospitalised patients: A multicentre study","authors":"Lily Annisa, Nurfina Dian Kartikawati, V. Ningrum","doi":"10.46542/pe.2024.243.286291","DOIUrl":null,"url":null,"abstract":"Background: Anticoagulants are indicated for several types of diseases with progression related to coagulation. Patients administered this drug need to be evaluated by the pharmacist regarding its effectiveness and possible side effects. \nObjective: This research aimed to analyse the profile use of anticoagulants among patients at Yogyakarta Hospital. \nMethod: This research was a multicentre study conducted retrospectively using the medical records of inpatients who received anticoagulants. \nResult: Among a total of 486 respondents, the majority were male (63.58%), and the adult age category (18-59 years) was 55.76%. Most anticoagulants were used in cases of cardiovascular disease, diagnosed with NSTEMI as much as 20.21%. The most used anticoagulant drug was heparin (48.9%), followed by fondaparinux (34.3%) and enoxaparin (16.8%). The most duration of anticoagulant use was one to four days (73.02%) with the dose range being 200-1000 units/day. \nConclusion: Heparin was the anticoagulant widely used in patients with NSTEMI. Although the elderly were the group most at risk of ADR due to anticoagulants, most of these drugs were precisely taken by adults, who also required serious attention. Further research is needed to provide a more comprehensive approach to anticoagulant therapy.","PeriodicalId":19944,"journal":{"name":"Pharmacy Education","volume":null,"pages":null},"PeriodicalIF":0.5000,"publicationDate":"2024-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pharmacy Education","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.46542/pe.2024.243.286291","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"EDUCATION, SCIENTIFIC DISCIPLINES","Score":null,"Total":0}

引用次数: 0

Abstract

Background: Anticoagulants are indicated for several types of diseases with progression related to coagulation. Patients administered this drug need to be evaluated by the pharmacist regarding its effectiveness and possible side effects. Objective: This research aimed to analyse the profile use of anticoagulants among patients at Yogyakarta Hospital. Method: This research was a multicentre study conducted retrospectively using the medical records of inpatients who received anticoagulants. Result: Among a total of 486 respondents, the majority were male (63.58%), and the adult age category (18-59 years) was 55.76%. Most anticoagulants were used in cases of cardiovascular disease, diagnosed with NSTEMI as much as 20.21%. The most used anticoagulant drug was heparin (48.9%), followed by fondaparinux (34.3%) and enoxaparin (16.8%). The most duration of anticoagulant use was one to four days (73.02%) with the dose range being 200-1000 units/day. Conclusion: Heparin was the anticoagulant widely used in patients with NSTEMI. Although the elderly were the group most at risk of ADR due to anticoagulants, most of these drugs were precisely taken by adults, who also required serious attention. Further research is needed to provide a more comprehensive approach to anticoagulant therapy.

查看原文本刊更多论文

住院病人抗凝药物的使用：一项多中心研究

背景：抗凝剂适用于多种与凝血功能有关的疾病。使用这种药物的患者需要由药剂师对其有效性和可能的副作用进行评估。研究目的本研究旨在分析日惹医院患者使用抗凝血剂的概况。研究方法本研究是一项多中心研究，使用接受抗凝药物治疗的住院患者的医疗记录进行回顾性分析。研究结果在总共 486 名受访者中，男性占大多数（63.58%），成年人（18-59 岁）占 55.76%。大多数抗凝药物用于心血管疾病病例，确诊为 NSTEMI 的高达 20.21%。使用最多的抗凝药物是肝素（48.9%），其次是磺达肝素（34.3%）和依诺肝素（16.8%）。使用抗凝药物最多的时间为一至四天（73.02%），剂量范围为 200-1000 单位/天。结论肝素是 NSTEMI 患者广泛使用的抗凝剂。虽然老年人是抗凝药物所致不良反应的高危人群，但这些药物中的大多数恰恰是由成年人服用的，他们也需要引起高度重视。需要进一步开展研究，为抗凝治疗提供更全面的方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Pharmacy Education EDUCATION, SCIENTIFIC DISCIPLINES-

CiteScore

0.80

自引率

20.00%

发文量

174

期刊介绍： Pharmacy Education journal provides a research, development and evaluation forum for communication between academic teachers, researchers and practitioners in professional and pharmacy education, with an emphasis on new and established teaching and learning methods, new curriculum and syllabus directions, educational outcomes, guidance on structuring courses and assessing achievement, and workforce development. It is a peer-reviewed online open access platform for the dissemination of new ideas in professional pharmacy education and workforce development. Pharmacy Education supports Open Access (OA): free, unrestricted online access to research outputs. Readers are able to access the Journal and individual published articles for free - there are no subscription fees or ''pay per view'' charges. Authors wishing to publish their work in Pharmacy Education do so without incurring any financial costs.