Drug utilisation study of parenteral nutrition in neonate patients

IF 0.5 Q4 EDUCATION, SCIENTIFIC DISCIPLINES

Pharmacy Education Pub Date : 2024-05-13 DOI:10.46542/pe.2024.243.310314

A. D. Puspitasari, Satya Andiva, Hargus Haraudi Barkah, Mahendra Tri Arif Sampurna, Budi Suprapti, Mariah Ulfa, Diah Sukmawati Pangarsih, Widia Yuniarti

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Abstract

Background: The neonatal period is an individual adaptation with a higher risk of death and complications. Using parenteral nutrition to meet nutritional imbalances in neonates requires close supervision to prevent complications caused by inappropriate administration. Objective: This study aims to examine the effectiveness of parenteral nutrition (PN) in weight changes, patient caloric balance, osmolarity, and side effects. Methods: This study used a prospective observation method and was carried out from April to June 2023 at Universitas Airlangga Hospital. Data were obtained through medical records and direct observation of the patient’s condition after the patient’s parents signed an informed consent. Data analysis was carried out descriptively. Results: PN was given centrally or peripherally to 71 patients. Of those, 21 were low birth weight patients. Caloric balance was achieved in almost all patients. All patients gained weight, although only 20.89% experienced a return to birth weight. Phlebitis occurred in 35.22% of patients. Conclusion: Parenteral nutrition is efficacious in increasing the patient’s weight, depending on the suitability of the calculation between calories needed and calories obtained and the osmolarity of the preparation.

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新生儿肠外营养药物使用研究

背景：新生儿期是个体适应期，死亡和并发症风险较高。使用肠外营养来解决新生儿的营养失衡问题需要严密的监护，以防止用药不当引起并发症：本研究旨在探讨肠外营养（PN）在体重变化、患者热量平衡、渗透压和副作用方面的有效性：本研究采用前瞻性观察法，于 2023 年 4 月至 6 月在 Universitas Airlangga 医院进行。在患者父母签署知情同意书后，通过病历和对患者病情的直接观察获取数据。数据分析以描述性方式进行：71名患者接受了中心或外周静脉输液。结果：71 名患者接受了中心或外周营养支持治疗，其中 21 名是低出生体重儿。几乎所有患者都实现了热量平衡。所有患者的体重都有所增加，但只有 20.89% 的患者恢复到了出生时的体重。35.22%的患者发生了静脉炎：结论：肠外营养对增加患者体重很有效，这取决于所需热量和所获热量之间的计算是否合适以及制剂的渗透压。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Pharmacy Education EDUCATION, SCIENTIFIC DISCIPLINES-

CiteScore

0.80

自引率

20.00%

发文量

174

期刊介绍： Pharmacy Education journal provides a research, development and evaluation forum for communication between academic teachers, researchers and practitioners in professional and pharmacy education, with an emphasis on new and established teaching and learning methods, new curriculum and syllabus directions, educational outcomes, guidance on structuring courses and assessing achievement, and workforce development. It is a peer-reviewed online open access platform for the dissemination of new ideas in professional pharmacy education and workforce development. Pharmacy Education supports Open Access (OA): free, unrestricted online access to research outputs. Readers are able to access the Journal and individual published articles for free - there are no subscription fees or ''pay per view'' charges. Authors wishing to publish their work in Pharmacy Education do so without incurring any financial costs.