Simulation and modeling of high-sensitive JL-TFET based biosensor for label free detection of biomolecules

Pratikhya Raut, Deepak Kumar Panda, Umakanta Nanda, Chih-Chieh Hsu
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Abstract

A biosensor employing a junctionless TFET (JL-TEFT) to identify different protein molecules is modelled and investigated in this paper. The JLTFET is chosen for designing the biosensor because of its superiority over TFET and JLFET. The biomolecules can be captured in this type of devices by creating cavities across the gate. Various output parameters of label free biosensing with respect to various dielectric constants was studied using TCAD simulator. This article further portrays current and voltage sensitivity. This paper also investigates the fill factor impact of size of biomolecules and cavity positioning on the performance of biosensor. The dielectric modulation method for identifying a range of proteins and amino acids is being investigated through simulations. The sensitivity of JLTFET-based biosensors was found to be 1013. The novelties in this manuscript is that for the first time, an analytical mathematical model of a triple material gate asymmetrical hetero-dielectric JLTFET biosensor has been derived here. The developed model is not having any empirical parameter. Hence the proposed model is faster. Besides exhibiting increased sensitivity when compared to previous FET and TFET-based biosensors, this device also shows its suitability for low-power applications, hence providing a multitude of avenues for future exploration.

Abstract Image

基于 JL-TFET 的高灵敏度生物传感器的仿真与建模,用于无标记生物分子检测
本文对一种采用无结 TFET(JL-TEFT)来识别不同蛋白质分子的生物传感器进行了建模和研究。之所以选择 JLTFET 设计生物传感器,是因为它优于 TFET 和 JLFET。通过在栅极上形成空腔,生物分子可以被捕捉到。使用 TCAD 模拟器研究了无标记生物传感的各种输出参数与各种介电常数的关系。本文进一步描述了电流和电压灵敏度。本文还研究了生物分子大小和空腔定位对生物传感器性能的填充因子影响。通过模拟研究了用于识别一系列蛋白质和氨基酸的介电调制方法。结果发现,基于 JLTFET 的生物传感器的灵敏度为 1013。本手稿的新颖之处在于首次推导出了三重材料栅非对称异质介电 JLTFET 生物传感器的分析数学模型。所建立的模型没有任何经验参数。因此,所提出的模型速度更快。与以前基于 FET 和 TFET 的生物传感器相比,该器件除了灵敏度更高之外,还显示出其适合低功耗应用,因此为未来的探索提供了多种途径。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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