Numerical investigation of planar microcoils integrated in microfluidic devices for biological applications

Abdelghani Benbrahim, Halima Benchenane, Salim Hammar, Benaoumeur Aour, Nasreddine Mekkakia-Maaza
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Abstract

The objective of this work is to create a finite element model of different magnetic actuator topologies using COMSOL Multiphysics software. The aim is to simulate and improve the magnetic field generated by different planar microcoil topologies while minimising energy dissipation. The magnetic field generated by square and circular spiral planar microcoils was compared with that produced by serpentine meander planar microcoils. It has been found that the trapping efficiency in a magnetic manipulation microfluidic system for biological applications is closely linked to the geometry and electrical parameters of the planar microcoils. In addition, the location of these microcoils within the microfluidic channel intended for the circulation of the paramagnetic microbeads also play a crucial role. The obtained results show that bu reducing the inter-turn spacing using a thinner conductor cross-section and injected a higher electrical intensity in the actuator, both the magnetic field strength and its gradient can be increased, and therefore cause a higher magnetic actuation force.

Abstract Image

用于生物应用的微流体设备中集成平面微线圈的数值研究
这项工作的目的是使用 COMSOL Multiphysics 软件创建不同磁致动器拓扑结构的有限元模型。目的是模拟和改进不同平面微线圈拓扑结构产生的磁场,同时尽量减少能量耗散。方形和圆形螺旋平面微线圈产生的磁场与蛇形蜿蜒平面微线圈产生的磁场进行了比较。研究发现,用于生物应用的磁操控微流控系统的捕获效率与平面微线圈的几何形状和电气参数密切相关。此外,这些微线圈在用于顺磁微珠循环的微流体通道中的位置也起着至关重要的作用。研究结果表明,使用较薄的导体截面减小线圈间距,并在致动器中注入较高的电强度,可以增加磁场强度及其梯度,从而产生较高的磁致动力。
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